The effect of repeated remote ischaemic postconditioning on infarct size in stroke patients.
- Conditions
- Stroke, CVA, herseninfarct
- Registration Number
- NL-OMON21188
- Lead Sponsor
- Radboudumc, Nijmegen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 200
Inclusion Criteria
Informed consent
- Age >18 years
Exclusion Criteria
Unstable vital signs
Admitted >24 hours after onset of symptoms
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To examine the impact of repeated daily remote ischaemic postconditioning, starting on the day of an ischaemic stroke on infarct size after 4 days or at the end of hospitalization (using MRI).
- Secondary Outcome Measures
Name Time Method Explore the effect of repeated daily remote ischaemic postconditioning on clinical outcome after 12 weeks (using the modified ranking score; degree of disability/dependence).<br><br /><br /><br>Assess the impact of repeated daily remote ischaemic postconditioning on validated and frequently used markers of vascular, immune, and anti-inflammatory pathways, and relate these effects to total infarct size and clinical outcome.