A prospective randomised controlled study:comparing intravenous and nebulised Dexmedetomidine in awake fibreoptic nasotracheal intubation
试验速览
- 阶段
- 2/3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 46
- 试验地点
- 1
- 主要终点
- To assess the sedation score after drug infusion and vocal cord movements for attempting awake fibreoptic intubation
研究概览
简要总结
Awake fibreoptic intubation is considered the gold standard for the management of difficult airway
It is best performed with the patient awake to maintain spontaneous ventilation Dexmedetomidine has been successful in AFOI due to its diverse actions such as it’s sedative, hypnotic, anxiolytic, analgesic, anti-sialagogue and sympatholytic properties and ability to provide anterograde amnesia and promote cardiac, respiratory and neurological stability
This study can be helpful as a technique of attempting fibreoptic intubation in patients having difficult airway, less mouth opening, cervical fractures, inability to extend neck
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 75.00 Year(s)（—）
- 性别
- All
入选标准
- •1.ASA grade 1 and 2 2.Patients undergoing elective surgeries under general anaesthesia 3.Posted for surgery requiring supine position only.
排除标准
- •1.Patient refusal 2.Pregnancy 3.Emergency surgeries 4.Hemodynamically unstable patients 5.Patient with liver and kidney diseases, liver cirrhosis, thrombocytopenia, coagulopathies.
结局指标
主要结局
To assess the sedation score after drug infusion and vocal cord movements for attempting awake fibreoptic intubation
时间窗: To assess hemodynamic responses at baseline, 2 minutes,4 minute,6 minutes, 8 minutes and 10 minutes after infusion and sedation score 10 minutes after drug infusion and vocal cord movements for attempting awake fibreoptic intubation
次要结局
- Hemodynamic responses to intubation(Outcome assessed at)
研究者
Dr Subhash Dahiya
Lala lajpat rai memorial medical College, Meerut