Enhancing Cancer Prevention and Control Pathways-Native Health Initiative
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 508
- 试验地点
- 2
- 主要终点
- Aim 3, Focus Groups, Descriptive: Knowledge, Barriers and Support, and Communication About Breast, Cervix, and Colorectal Cancers
研究概览
简要总结
There are continued disparities in cancer incidence, mortality, and survival between American Indians (AIs) and Whites on cancers responsive to early screening (i.e., breast, colorectal, and cervical) in the US. In New Mexico (NM), AIs compared with other racial/ethnic populations are significantly less likely to adhere to recommended screening guidelines. The purpose of this trial is to develop and pilot test multilevel/multicomponent intervention strategies to enhance screening for breast, colorectal, and cervical cancers.
详细描述
There are continued disparities in cancer incidence, mortality, and survival between American Indians (AIs) and Whites on cancers responsive to early screening (i.e., breast, colorectal, and cervical) in the US. Between 1990-2009, based on data from Contract Health Service Delivery Area Counties across the US, the mortality-to-incidence ratios for these cancers were significantly higher for American Indian/Alaska Natives compared to Whites (breast: 1.22, colorectal: 1.16, cervix: 1.36), indicating poorer survival. New Mexico (NM) AIs also experience substantial cancer disparities. Between 2010-2014, AIs compared to Whites had higher incidence (per 100,000) for cervical (7.9 vs. 6.9) and colorectal (male: 46.5 vs. 35.2; female: 29.2 vs. 28.2) cancers, and higher mortality for cervical (3.7 vs. 1.3) and colorectal (males only; 18.9 vs. 15.6) cancers. AIs were more likely to receive a late-stage (i.e., regional or distant) cancer diagnosis for all 3 screen detectable cancers. AIs have some of the lowest cancer screening rates compared with other racial/ethnic groups. In NM, AIs listed in the Indian Health Service (IHS) Albuquerque Area have substantially lower screening rates than the state's White population do. AIs had screening rates of: breast (58.5%, women ages 52-64), colorectal (41.9%, ages 50-75), and cervical (63.9%, women ages 24-64) cancers; whereas, screening rates for Whites were: breast (70.0%, ages 50-74), colorectal (69.2%, ages 50-75), and cervical (77.8%, women 21-65)
The overall objective is to develop and pilot test culturally and linguistically appropriate interventions to enhance age- and risk-appropriate breast, colorectal, and cervical cancer screening in concordance with the U.S. Preventive Services Task Force recommended guidelines
Aim 3 (Focus Groups, Descriptive): Qualitative documentation of perspectives on cancer control needs in the Zuni Pueblo
Protocol: Aim 3 (Focus Groups, Descriptive): Qualitative documentation of perspectives on cancer control needs in the Zuni Pueblo
- Research Design: Focus groups that gather qualitative (descriptive) perspectives and insights from a small group of participants
- Research Setting: Zuni Pueblo
- Participant identification and sampling: Non-probability sampling
- Procedures: The investigators will contact interested participants for focus group sessions
- Primary Outcome: Knowledge about, barriers and support for, and communication about breast, cervix, and colorectal cancers
- Data Analysis: Thematic analyses of transcripts of the focus group discussions
- Sample Size Considerations: The investigators will enroll about 8-10 participants per focus group
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Screening
- 盲法
- None
入排标准
- 年龄范围
- 21 Years 至 75 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Breast Cancer Screening Intervention
- •Women age 45-75
- •Average risk for breast cancer
- •Never had a mammogram OR not had a mammogram within the past 2 years
- •Residing in the Zuni Pueblo
排除标准
- •Breast Cancer Screening Intervention. Meeting at least one of the following criteria:
- •Women with breast implants, pregnant, or breast feeding
- •History of breast cancer
- •Have new breast complaints such as lump or nipple discharge
- •Inclusion Criteria: Colorectal Cancer Screening Intervention
- •Men and women aged 45-75
- •Average risk for colorectal cancer
- •Never had a fecal occult blood test (FOBT), or fecal immunochemical test (FIT) or a colonoscopy OR not had a FOBT or FIT in the past year, OR no colonoscopy in the past 10 years
- •Residing in the Zuni Pueblo
- •Exclusion Criteria: Colorectal Cancer Screening Intervention. Meeting at least one of the following criteria:
- •History of colorectal cancer, total colectomy, adenomatous polyps, or inflammatory bowel disease
- •Up-to-date with colorectal cancer screening
- •Severe comorbidity
- •Incarceration
- •Family history of colorectal cancer
- •Hospice/terminal care status
- •Inclusion Criteria: Cervical Cancer Screening Intervention
- •Women aged 21-65
- •Never had a cytology (Pap smear) OR had a Pap smear more than 3 years ago OR women aged 30-75, and never had screening with a combination of cytology and human papillomavirus testing OR no combination of testing in the past 5 years
- •Residing in the Zuni Pueblo
- •Exclusion Criteria: Cervical Cancer Screening Intervention. Meeting at least one of the following criteria:
- •History of total hysterectomy
- •High risk for cervical cancer due to suppressed immune system (e.g., HIV infection, organ transplant, long-term steroid use)
- •Women over age 65 who have had regular screenings with normal results
结局指标
主要结局
Aim 3, Focus Groups, Descriptive: Knowledge, Barriers and Support, and Communication About Breast, Cervix, and Colorectal Cancers
时间窗: 12 months
The focus group discussion documents the participants' knowledge about, barriers and support for, and communications about cancer and cancer prevention. Focus group methodology is primarily a qualitative research method and directly quantifying themes is not the typical approach. In this research, only qualitative data were collected with no quantification other than of the number of participants that endorsed a particular theme
Aim 4, Community Survey, Descriptive: Cancer Control Needs
时间窗: 7 months
Age/gender specific self-reported screening behaviors for breast, colorectum, and cervical cancers
Aim 8, INT, Pilot Test: Age/Gender-specific Breast, Colorectal, and Cervical Cancer Screening
时间窗: 8 months
Self-reported receipt of a screening exam, or scheduling an appointment for a screening exam, or self-reported attempt to make an appointment for a screening exam. Cancer-specific screening exams included FOBT/FIT/Colonoscopy for colorectal cancer for men and women 45-75 years, Pap smear for cervical cancer for women 21-75 years, or mammogram for breast cancer for women 45-75 years
次要结局
未报告次要终点
