To compare the efficacy of Nitazoxanide in a single dose of 3g VO and metronidazole in a single dose of 2g in the eradication of T. vaginalis.

Not Applicable

• Conditions: -A59 Trichomoniasis; Trichomoniasis; A59

• Registration Number: PER-009-02
• Lead Sponsor: ASOCIACION BENEFICA PRISMA,

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2002-01-14
• Last Update Posted: 4 September 2023

Recruitment & Eligibility

• Status: Complete
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

• Patients 18 years of age or older, with vaginal discharge.
• Presence of mobile trichomonads in direct examination with saline or culture Positive to T. vaginalis or Polymerase Chain Reaction Test (PCR) positive for T. vaginalis in the 5 days prior to inclusion in the study.
• Written informed consent of the patient or her legal representative.
• Patients of reproductive age must also have a pregnancy test in negative urine in the 48 hours prior to the start of the clinical study.

Exclusion Criteria

• Diagnosis of Vulvovaginal Candidiasis by identification of pseudohyphae in
the direct examination.
• Diagnosis of Bacterial Vaginosis by observation of clue cells in the
direct examination.
• Having received a derivative of S-nitroimidazoIe (metronidazole, tinidazole,
ornidazole or secnidazole) or treatment with nitazoxanide in a period of 14 days
prior to randomization.
• History of hypersensitivity to nitazoxanide or metronidazole.
• Pregnancy.

Study & Design

• Study Type: Interventional
• Study Design: Not specified