Development of a CT-Derived Risk Score to Guide Treatment Decision: Tracheal Stenosis Morphology and Attenuation Score (TSMAS)
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 80
- 主要终点
- Prediction of Surgical Requirement Based on Tracheal Diameter on Initial CT
研究概览
简要总结
This study aims to develop a CT-based scoring system to help predict whether patients with tracheal stenosis will require surgical treatment or can be managed with endoscopic procedures. Using retrospective data, researchers will evaluate CT scans of patients diagnosed with tracheal stenosis to measure features such as airway diameter, wall thickness, and tissue density (measured in Hounsfield Units). The goal is to create a non-invasive, reproducible, and objective tool-called the Tracheal Stenosis Morphology and Attenuation Score (TSMAS)-that can support clinical decision-making and improve treatment planning.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age ≥ 18 years
- •Diagnosed with tracheal stenosis
- •Underwent thoracic CT imaging at the time of diagnosis
- •CT scans available in adequate quality and in DICOM format
- •No prior surgical treatment for tracheal stenosis before CT imaging
排除标准
- •Tracheal stenosis due to malignancy, foreign body, or tracheobronchial tumors
- •History of tracheal surgery before CT imaging
- •Poor quality CT images (e.g., motion artifacts, incomplete tracheal segments)
- •Patients with a history of radiotherapy (RT) to the neck or mediastinum
结局指标
主要结局
Prediction of Surgical Requirement Based on Tracheal Diameter on Initial CT
时间窗: From initial diagnosis to surgical decision (up to 12 months)
Evaluation of whether smaller tracheal diameter on initial CT is associated with need for surgery. Unit of Measure: millimeters
Prediction of Surgical Requirement Based on HU Values of the Stenotic Segment on CT
时间窗: From initial diagnosis to surgical decision (up to 12 months)
Evaluation of whether high HU values in the stenotic segment predict surgical need. Unit of Measure: Hounsfield Units (HU)
Prediction of Surgical Requirement Based on Tracheal Wall Thickness on Initial CT
时间窗: From initial diagnosis to surgical decision (up to 12 months)
Evaluation of whether increased tracheal wall thickness on initial CT predicts surgical need. Unit of Measure: millimeters
次要结局
未报告次要终点
研究者
Caner İşevi, MD
Principal Investigator
Ondokuz Mayıs University