Critical Flicker-Fusion Frequency as a Method for Quantification of Neurotoxic Side Effects of Anticonvulsive Drugs

• Conditions: G40.2; G40.3; Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures; Generalized idiopathic epilepsy and epileptic syndromes

• Registration Number: DRKS00024426
• Lead Sponsor: Epilepsiezentrum Kork

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-02-05
• Study Completion: 2021-09-30
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 67

Inclusion Criteria

• Age between 18 and 70 years in the inpatient treatment of our epilepsy center
• Diagnosis of epilepsy
• Drug treatment with anticonvulsants

Exclusion Criteria

• Incapable of consent or cooperation
• Epilepsy with photosensitivity
• Ophthalmic diseases
• Participants with a medical or psychiatric illness that the investigator believes could compromise or endanger their own health or the patient's ability to participate in the study; for example, patients with status epilepticus, acute psychosis, acute shortness of breath or participants with significant cognitive disorders etc.
• Parkinson's disease

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Critical Flicker Fusion Frequency (Hz) is frequency at which a light stimulus no longer perceived as flickering, but as continuous, is referred to as flicker fusion frequency (also critical flicker fusion frequency)

Secondary Outcome Measures

Name	Time	Method
Fusion frequency (Hz) (frequency of a light stimulus at which a continuous light is perceived as flicker.)