Randomized, Single-Blinded Study to Evaluate the Timing Effect of Ultrasound-Guided Paravertebral Block in Patients Undergoing Robotic Mitral Valve Repair Procedure
试验速览
- 阶段
- 不适用
- 入组人数
- 60
- 主要终点
- Durations of ICU and hospitalization
研究概览
简要总结
This study is to evaluate whether the administration of ultrasound-guided paravertebral block (PVB) after surgery would produce better postoperative pain control and fast postoperative recovery after Robotic cardiac surgery. Half of participants will receive PVB before surgery, while the other half will receive PVB at the end of surgery.
详细描述
Ultrasound-guided PVB (either before surgery, or after surgery) is the standard postoperative pain management for Robotic cardiac surgery. This technique is to inject local anesthetic (numb medication) around nerve to decrease pain. But the optimal time of PVB is unknown.
The administration of PVB before surgery can help pain control during the surgery and after surgery. But the duration of PVB could be reduced because surgery itself can last 5-6 hrs.
The PVB after surgery will not provide pain control during surgery, but may provide longer pain control after surgery, and may help participants faster recovery after surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Outcomes Assessor)
盲法说明
Outcomes assessor will be blinded to study group
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age ≥ 18 yrs
- •Either gender
排除标准
- •Refusal to participate in the study
- •Age< 18 yrs
- •Contraindications to regional blockage including but not limited to:
- •Patient refusal to regional blockade
- •Infection at the site of needle insertion
- •Systemic infection
- •Bleeding diathesis or coagulopathy
结局指标
主要结局
Durations of ICU and hospitalization
时间窗: 2-6 days
Duration (days) of ICU stay, and duration of hospital stay
次要结局
- Pain intensity measure(2-3 days)
研究者
Manxu Zhao
Principal Investigator
Cedars-Sinai Medical Center