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Clinical Trials/NCT05903599
NCT05903599
Completed
Not Applicable

Effects of Anodal Transcranial Direct Current Stimulation on Postural Stability in Sub-Acute Stroke

Riphah International University1 site in 1 country36 target enrollmentMay 2, 2023
ConditionsStroke

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Stroke
Sponsor
Riphah International University
Enrollment
36
Locations
1
Primary Endpoint
Trunk impairment scale (TIS) for Stroke Patients
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

Stroke patients experience weakening of muscles on the affected side. Damage to the motor cortex and the pyramidal tract due to a stroke leads to a motor control disorders and co-contraction of trunk muscles due to abnormal levels of abdominal muscle tension and voluntary movement.

Detailed Description

TDCS is known to modulate motor excitability in humans and motor performance is crucial in postural control. Studies reports that applying anodal TDCS to the ipsilesional motor cortex improved motor functioning in which the Transcranial Direct Current Stimulation may have stimulated preserved areas of the motor cortex to enhance synaptic efficiency along the corticospinal tract. Anodal TDCS has been shown to have immediate and short-term effects in stroke but its long-term effects in stroke are still unclear. Additionally, the available literature focuses on acute and chronic stages of stroke so we will target subacute stage of stroke. Therefore, this study is designed to investigate the short and long-term effects of Anodal Transcranial Direct Current Stimulation on postural stability in subacute stroke.

Registry
clinicaltrials.gov
Start Date
May 2, 2023
End Date
January 31, 2024
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Ischemic stroke
  • Sub-acute stroke
  • Minimum score of 18 on PASS

Exclusion Criteria

  • Hearing and Visual loss/ deficit
  • Recurrent CVA
  • Neurological condition affects the cognition
  • Wound at skull
  • Presence of shunt and/or metallic implant at cranial region
  • Brain tumors
  • Musculoskeletal conditions/ surgery in the lower extremities
  • Cognitively compromised

Outcomes

Primary Outcomes

Trunk impairment scale (TIS) for Stroke Patients

Time Frame: 12th week

It evaluates motor impairment of the trunk after stroke. The TIS scores, on a range from 0 to 23, static and dynamic sitting trunkal stability as well as trunk coordination. It also score the quality of trunk movement and to be a guide for treatment. Number of items are 7, score of each item is 0-3.

Postural Assessment Scale for Stroke Patients (PASS)

Time Frame: 12th week

PASS evaluates the postural imbalance and functional abilities of patients with stroke in several conditions (lying on back, sitting, standing and while changing positions). This scale is composed of 12 items. Score can vary from 0 to 3, with 0 being the lowest level of functionality and 3 the highest; the total score be 36.

Secondary Outcomes

  • Stroke Specific Quality of life Scale (SS-QoL)(12th week)
  • Functional Reach Test (FRT)(12th week)
  • Timed Up and Go Test (TUG)(12th week)

Study Sites (1)

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