Study of Hemodynamic Conditions Measured During Hepatectomy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 9
- 试验地点
- 1
- 主要终点
- Liver vessel debit
研究概览
简要总结
Hepatocellular insufficiency is a dreaded complication after hepatectomy, since, if it is persistent, it leads to the death of the patient in the absence of liver transplantation.
The preoperative evaluation aims in particular to estimate the risk of postoperative hepatocellular insufficiency so as to minimize or contraindicate high-risk patients.
It has been shown that the flow of the portal vein is correlated with liver function, especially in the living donor and after portal embolization. More recently, the study of flow rates in the portal vein and the hepatic artery after transplantation has shown a correlation with the recovery of graft function.
The hypothesis is that portal and arterial flow after hepatectomy can predict postoperative hepatocellular function.
详细描述
Measurements of flow rates in the portal vein and the hepatic artery by different transit times are available thanks to the Medistim VeriQTM system that the investigators already use routinely in the context of liver transplantation when performing hepatectomies.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patient 18 years or more
- •Patient undergoing laparotomy for liver resection
排除标准
- •Patient under tutorship or curatorship
- •Pregnant or lactating woman
- •Difficulties in understanding French
- •Patient operated by laparoscopy
- •Patient having objected to the processing of his data
结局指标
主要结局
Liver vessel debit
时间窗: Baseline
Mesure of liver debit during hepatectomy
次要结局
未报告次要终点