NCT03529994
Completed
Not Applicable
Work of Breathing and Oxygen Saturation Stability in Infants With Respiratory Insufficiency While Receiving Various Flow Rates of High Flow Nasal Cannula
ConditionsHigh Flow Nasal Cannula
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- High Flow Nasal Cannula
- Sponsor
- Christiana Care Health Services
- Enrollment
- 30
- Locations
- 1
- Primary Endpoint
- Work of breathing indices
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
The purpose of this study is to compare work of breathing on different levels of high flow respiratory support on infants born between 27 and 37 weeks gestation.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Infants between 27 and 37 weeks corrected gestational age
- •\>4 days PNA
- •Stable (i.e. not meeting exclusion criteria) and receiving non-invasive respiratory support (HFNC) for ≥ 12 hours
- •Requiring ≤ 40% supplemental FiO2 as determined by the clinical care team for clinical care purposes independent of this study
Exclusion Criteria
- •Infants with skeletal, neuromuscular, or abdominal surgical disorders that affect the accuracy of WOB measurements
Outcomes
Primary Outcomes
Work of breathing indices
Time Frame: 2 hours
Altering HFNC flow rates and its effect on work of breathing indices in preterm infants with respiratory insufficiency.
Secondary Outcomes
- Intermittent hypoxia(2 hours)
Study Sites (1)
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