Comparing the Effectiveness of Cyanoacrylate Tissue Adhesives and Conventional Sutures in the Closure of Intraoral Surgical Wounds- A Randomized Clinical Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 20
- 试验地点
- 2
- 主要终点
- Postoperative pain
研究概览
简要总结
This study compares the effectiveness of two materials used for intraoral wound closure after removal of impacted mandibular third molar tooth. One Group received braided black silk suture and the other group received N-butyl 2-octyl cyanoacrylate tissue adhesives.
详细描述
Conventional method of wound closure after removal of impacted mandibular molar is by suturing the wound using braided black silk suture and allowing for primary healing. Suturing in the most posterior region of oral cavity is not easy, it requires more time and additional skills as well. Patient has to come for a second visit for removal of suture. Moreover tight sutures may lead to ischemia and necrosis.
Tissue adhesives adopts the idea of sutureless wound closure. They are even sloughed off from the surface of mucosa 7 days after the application.
This study compares the effectiveness of conventional sutures and tissue adhesives in closure of intraoral surgical wounds after removal of mandibular third molar.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 17 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •patients requiring surgical removal of mesioangular, position A impacted mandibular third molar
- •clean incisions approximately 2-3 cms in length which can be approximated
- •Healthy (ASAI) or patients with mild systemic disease no functional limitations
- •Patients not allergic to the drugs or anesthetic agents used in the surgical protocol
排除标准
- •Patients taking any medications that influences wound healing
- •Patients on non steroidal anti inflammatory drugs
- •uncooperative patients patients allergic to cyanoacrylate
结局指标
主要结局
Postoperative pain
时间窗: 4th postoperative day
A 10 mm Numerical rating scale assessing postoperative pain. Possible score ranges from 0 (no pain) to 10 (worst possible pain).
postoperative pain
时间窗: 5th postoperative day
A 10 mm Numerical rating scale assessing postoperative pain. Possible score ranges from 0 (no pain) to 10 (worst possible pain).
wound healing
时间窗: 7th postoperative day
A 5 point early wound healing scale assessing wound healing after 7 postoperative days.
次要结局
未报告次要终点
研究者
Abdul Kalam Azad
Assistant Professor
Melaka Manipal Medical College