effect of platelet-rich plasma(PRP)on fertility in wome
Phase 2
- Conditions
- oninflammatory disorder of female genital tract.Complication associated with artificial fertilization ,unspecified
- Registration Number
- IRCT20180417039338N2
- Lead Sponsor
- Babol University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 30
Inclusion Criteria
Healthy women between 18 and 40 years old
BMI below 30 kg / m 2
Have at least 3 or more unsuccessful fetal transmissions
Fetal removal candidate
Exclusion Criteria
Hemoglobin disorders (hemoglobin less than 11 mg / ml and platelet below 150,000)
Immunological disorders
Hormonal disorders of genetic and chromosomal anomalies
Acute infection
Uterus anomalies including the unicorn uterus (whether or not surgical) arcuate
History of uterine enzymes such as myomectomy and cesarean section
NSAID use within 10 days before intervention
Corticosteroid use over the past 1 month
Smoking
Fever
History of malignancy
Coagulation disorder
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Fetal Vision Imaging. Timepoint: Week 5 after ET. Method of measurement: Vaginal ultrasound.;Fetal heartburn. Timepoint: Week 5 after ET. Method of measurement: Vaginal ultrasound.;Endometrial thickness. Timepoint: in 10th day of cycles and 72 hr after infusion of PRP. Method of measurement: Trans vaginal sonography.
- Secondary Outcome Measures
Name Time Method Determine the amount of implantation. Timepoint: 4week after embryo transfer. Method of measurement: Trans vaginal sonography.;Clinical pregnancy or miscarriage. Timepoint: 4week after embryo transfer. Method of measurement: Trans vaginal sonography.