A double-blind, Randomized, Controlled trial comparison of a topical piroxicom plus metronidazole gel and Piroxicom gel in Treatment for Periodontal disease.

Phase 2

Conditions: Periodontal disesaes.
Periodontal disesaes

Registration Number: IRCT2014050817587N3

Lead Sponsor: Deputy of Research Council of Dental Branch Islamic Azad University of Tehran

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: All

Target Recruitment: 20

Inclusion Criteria

All of the Patients following criteria were included in the study: aged between 30 and 45 years; 20 natural teeth present; Probing depth (PD) of 4-6 mm)

Patients were Excluded from the Study if they met one or more of the Following criteria: Existing systemic disease that may influence the severity or progression of periodontitis, or Diabetes Mellitus; Taking medications that may influence the periodontium (e.g. Phenytoin, ... or Non-steroidal anti-Inflammatory drugs) or other medicines (Antibiotic) within the 6 months preceding the beginning of the study, Orthodontic treatments; Extensive dental restorations, Pregnancy or Lactation; Non-agreement with the examination and treatment appointments; Mouthrinses, During the entire period of the Study; Hypersensitive to these medicine; Smoking

Exclusion Criteria

Not provided

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pocket depth. Timepoint: Reduction of Pocket depth. Method of measurement: Periodontal probe.;Clinical attachment level. Timepoint: 15 days. Method of measurement: Periodontal probe.

Secondary Outcome Measures

Name	Time	Method
Reduction of bleeding on probing. Timepoint: 15 days. Method of measurement: Periodontal probe.;Reduction of plaque index. Timepoint: 15 days. Method of measurement: Plaque Index(O’Leary ).