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临床试验/ISRCTN11742127
ISRCTN11742127已完成未知

Efficacy of mechanical scaling and root planning and adjunctive chemotherapy (doxycycline hyclate 20 mg) on systemic health improvement in diabetics

King Abdulaziz City for Science and Technology (Saudi Arabia)0 个研究点目标入组 346 人开始时间: 2008年6月25日最近更新:
适应症

试验速览

阶段
未知
状态
已完成
发起方
入组人数
346

研究概览

简要总结

2010 results in: https://doi.org/10.1016/j.ijdm.2010.08.006 (added 04/06/2019)

研究设计

研究类型
Interventional

入排标准

性别
All

入选标准

  • 1. Both males and females, age range 18-65 years old
  • 2. Diabetes, identified as type 1 or 2
  • 3. Have had diabetes for at least 1 year
  • 4. Diabetes is under control by oral hypoglycemic agent or insulin or both
  • 5. Have been on the same type and dose of diabetic medication for the past 6 months
  • 6. Good physical condition with no serious medical conditions or transmittable disease i.e. malignant disease, active hepatitis, free from any cardiac condition that needs antibiotic prophylaxis prior to teeth scaling and root planning
  • 7. Have minimum of 18 remaining natural and non-capped teeth
  • 8. Have minimum of 6 sites in minimum of 2 different quadrants with probing pocket depth (PPD) >=5 mm but <=8 mm
  • 9. Have not had treatment with SRP within 6 months prior to baseline visit
  • 10. Visible supragingival calculus in minimum of 4 teeth in 2 different quadrants
  • 11. Absence of orthodontic bands and brackets and/or dental appliances that would affect scored indices

排除标准

  • 1. Use of antibiotics within three months prior to baseline appointment
  • 2. Pregnant or nursing female subjects

研究者

发起方
King Abdulaziz City for Science and Technology (Saudi Arabia)

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