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Iron Dextran Versus Oral Iron for Treating Iron Deficiency Anemia in Pregnant Women

Phase 3
Completed
Conditions
Anemia
Interventions
Registration Number
NCT03212781
Lead Sponsor
Assiut University
Brief Summary

Iron deficiency is the most prevalent nutritional deficiency and the most common cause of anemia .It is characterized by a defect in hemoglobin synthesis, resulting in red blood cells that are abnormally small (microcytic) and contain a decreased amount of hemoglobin (hypochromic).

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
Female
Target Recruitment
66
Inclusion Criteria
  • Hemoglobin < 10 g/dL
  • Gestational age between 14-28 weeks.
  • Willingness to participate and signing the informed consent form.
Exclusion Criteria
  • Iron overload or disturbances in utilization of iron
  • Decompensated liver cirrhosis and active hepatitis
  • Active acute or chronic infections
  • History of multiple allergies
  • Known hypersensitivity to parenteral iron or any recipients in the investigation drug products
  • Erythropoietin treatment within 8 weeks prior to the screening visit
  • Other iron treatment or blood transfusion within 4 weeks prior to the screening visit
  • Planned elective surgery during the study.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
oral ironFerrous Fumaratepatients will receive oral iron
intravenous ironIron dextranpatients will receive intravenous iron as total dose infusion
Primary Outcome Measures
NameTimeMethod
The change in Hemoglobin concentration from baseline to 8 weeks therapy8 weeks

measure hemoglobin level before and after treatment

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Assiut Faculty of Medicine

🇪🇬

Assiut, Egypt

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