NCT01946451
Unknown
Not Applicable
Gene Expression and Their Correlations in Patients With Idiopathic and Secondary Epiretinal Membranes in Proliferative Diabetic Retinopathy
ConditionsProliferative Diabetic Retinopathy
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Proliferative Diabetic Retinopathy
- Sponsor
- Medical University of Silesia
- Locations
- 1
- Primary Endpoint
- Gene expression in patients with idiopathic and secondary epiretinal membranes in proliferative diabetic retinopathy.
- Last Updated
- 12 years ago
Overview
Brief Summary
The purpose of this study was to investigate the expression of selected genes both in epiretinal membranes (ERMs) and peripheral blood mononuclear cells (PBMCs) from patients with primary and secondary epiretinal membranes in proliferative diabetic retinopathy. Possible correlations between messenger ribonucleic acid (mRNA) levels of these genes were also identified.
Investigators
Dorota Romaniuk
MD
Medical University of Silesia
Eligibility Criteria
Inclusion Criteria
- •Caucasian race,
- •both males and females,
- •aged ≥ 55 years,
- •suffering from idiopathic ERMs or secondary ERMs in proliferative diabetic retinopathy (PDR).
- •Presence of ERM was proven in optical coherence tomography (OCT) examination.
- •Exclusion criteria:
- •aged \< 55 years,
- •systemic connective tissue disease,
- •active inflammatory process
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Gene expression in patients with idiopathic and secondary epiretinal membranes in proliferative diabetic retinopathy.
Time Frame: The period between the diagnosis of the ERMs and the actual surgery for the condition was between 2 and 43 months.
Study Sites (1)
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