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临床试验/NCT01946451
NCT01946451Unknown不适用

Gene Expression and Their Correlations in Patients With Idiopathic and Secondary Epiretinal Membranes in Proliferative Diabetic Retinopathy

Medical University of Silesia1 个研究点 分布在 1 个国家开始时间: 2012年6月最近更新:
适应症

试验速览

阶段
不适用
试验地点
1
主要终点
Gene expression in patients with idiopathic and secondary epiretinal membranes in proliferative diabetic retinopathy.

研究概览

简要总结

The purpose of this study was to investigate the expression of selected genes both in epiretinal membranes (ERMs) and peripheral blood mononuclear cells (PBMCs) from patients with primary and secondary epiretinal membranes in proliferative diabetic retinopathy. Possible correlations between messenger ribonucleic acid (mRNA) levels of these genes were also identified.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Retrospective

入排标准

年龄范围
55 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Caucasian race,
  • both males and females,
  • aged ≥ 55 years,
  • suffering from idiopathic ERMs or secondary ERMs in proliferative diabetic retinopathy (PDR).
  • Presence of ERM was proven in optical coherence tomography (OCT) examination.
  • Exclusion criteria:
  • aged < 55 years,
  • systemic connective tissue disease,
  • active inflammatory process

排除标准

  • 未提供

结局指标

主要结局

Gene expression in patients with idiopathic and secondary epiretinal membranes in proliferative diabetic retinopathy.

时间窗: The period between the diagnosis of the ERMs and the actual surgery for the condition was between 2 and 43 months.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Dorota Romaniuk

MD

Medical University of Silesia

研究点 (1)

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