The Effect of Standardized Enteral Nutrition on Critically Ill Patients
- Conditions
- Critically Ill
- Interventions
- Other: A standard enteral nutrition protocol
- Registration Number
- NCT02976155
- Lead Sponsor
- Second Affiliated Hospital, School of Medicine, Zhejiang University
- Brief Summary
The goal of this study is to evaluate whether a standard enteral nutrition protocol can improve the efficiency in achieving nutritional goals and improve prognosis in critically ill patients.
- Detailed Description
As investigators all know, the nutrition status in critically ill patients is associated with the prognosis of these patients. And it has been confirmed that early enteral nutrition results in better outcome. However,some epidemiological investigation reported that in most intensive care unit, the phenomenon of delayed feeding or under feeding are not uncommon. In 2007, a study reported that the percentage of early enteral nutrition within 48h is 64%, based on mechanical ventilated patients in 208 intensive care unit nationally. Other study indicated that the calorie supported by the enteral nutrition only constitute 50% of the target calorie. Several studies have showed that the application of a standard enteral nutrition protocol could result in an improvement in the delivery of enteral feedings to patients. However, there is no such study in China.The goal of this study is to evaluate whether a standard enteral nutrition protocol can improve the efficiency in achieving nutritional goals and improve prognosis in critically ill patients.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 439
- Critically ill patients who is expected the length of ICU stay for more than 3 days
- Patients who can obtain enough calorie through independent oral feeding. Patients aged less than 18 years. Patients who are pregnant or breastfeeding. Patients who are burned. Patients with malignant tumor terminal stages of diseases
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SEQUENTIAL
- Arm && Interventions
Group Intervention Description Post-intervention A standard enteral nutrition protocol The intervention in this arm is the application of a standard enteral nutrition protocol
- Primary Outcome Measures
Name Time Method The proportion of patients receiving enteral nutrition in patients receiving any type of nutrition 7 days after ICU admission The proportion of patients receiving parenteral nutrition in patients receiving any type of nutrition 7 days after ICU admission The proportion of patients receiving Enteral plus supplement parenteral in patients receiving any type of nutrition 7 days after ICU admission The time from hospital admission to the begain Enteral nutrition. 7 days after ICU admission The time from hospital admission to achieve the target calorie. 7 days after ICU admission
- Secondary Outcome Measures
Name Time Method ICU length of stay From date of the ICU admission until discharge form ICU,assessed up to 12 months Duration of mechanical ventilation. From date of the initiation of mechanical ventilation until weaning,assessed up to 12 months ICU fee. From date of the ICU admission until discharge form ICU,assessed up to 12 months The incidence of complications(Diarrhea , abdominal distension, nausea and vomiting.) From date of the ICU admission until discharge form ICU,assessed up to 12 months Hospital mortality. From date of the ICU admission until discharge form hospital,assessed up to 12 months ICU mortality. From date of the ICU admission until discharge form ICU,assessed up to 12 months
Trial Locations
- Locations (1)
The second affiliated hospital of Zhejiang university, school of medicine.
🇨🇳Hangzhou, Zhejiang, China