Effect of supplementation in treatment of depressio
Phase 3
- Conditions
- Depression.Depressive episode
- Registration Number
- IRCT201412065623N29
- Lead Sponsor
- Kashan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Patients with major depressive according to DSM-IV-TR criteria
Aged 18 to 65 years
The least score 15 on Hamilton Depression scoring system.
Exclusion Criteria
History of coronary infarction, angina pectoris, stroke or renal stone disease
Pregnant or lactating women
Smokers
Liver problems
Substance abuse
Non-normal creatinine concentrations
Taking dietary supplements during the last 2 months
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Depression. Timepoint: At the beginning of the study and after 8 weeks of intervention. Method of measurement: Questionnaire.
- Secondary Outcome Measures
Name Time Method Fasting plasma glucose. Timepoint: Baseline and End-of-trial. Method of measurement: Enzymatic.;Triglycerides. Timepoint: Baseline and End-of-trial. Method of measurement: Enzymatic.;Total antioxidant capacity. Timepoint: Baseline and End-of-trial. Method of measurement: Spectrophotometry.;Glutathione. Timepoint: Baseline and End-of-trial. Method of measurement: Spectrophotometry.;Cholesterol. Timepoint: Baseline and End-of-trial. Method of measurement: Enzymatic.;Insulin. Timepoint: Baseline and End-of-trial. Method of measurement: Elisa.