The Effects of a Single Bout of Moderate Intensity Aerobic Exercise Combined With Different Environments on Executive Function and Processing Speed in Individuals With TBI
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 24
- 试验地点
- 2
- 主要终点
- Change on N-Back Test (N-back)
研究概览
简要总结
Aerobic exercise is a promising treatment modality for cognition in persons with TBI, but effects are consistently small. This study aims to investigate the effect of difference environments during moderate intensity cycling sessions on cognition.
详细描述
The proposed research study would be the first to investigate the acute effects of aerobic exercise with different environments relative to control and comparison conditions on several domains of cognition in people with TBI. This critical investigation will be a first step toward systematically identifying an optimal exercise training intervention for managing common cognitive consequences of TBI.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- None
盲法说明
The PI will be blinded to the order of conditions for each participant.
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Be at least 18 years of age and younger than 59 years of age
- •Speak English as their primary language
- •Have had a previous TBI at least one year prior\
排除标准
- •Have contraindications to moderate or high intensity physical activity, based on the Physical Activity Readiness Questionnaire (PAR-Q)
- •Have a history of psychiatric illness (ex: major depression, bipolar disorder, schizophrenia), neurological disorders beyond TBI (ex: stroke, seizure disorder), or substance abuse
- •Currently use medications that might impact cognition (ex: steroids, benzodiazepines, neuroleptics)
- •Be currently pregnant
- •Have visual impairments not otherwise corrected by contact lenses (ex: stereo blindness, colorblindness)
- •Have a high likelihood of motion sickness
结局指标
主要结局
Change on N-Back Test (N-back)
时间窗: 30 minutes (before and after the acute exercise intervention)
The N-Back is a measure that requires participants to listen to a sequence of numbers and decide if the current number is the same as the one presented N trials ago.
Change on the Modified Flanker Test (MFT)
时间窗: 30 minutes (before and after the acute exercise intervention)
This task requires individuals to correctly respond to a target symbol amid other symbols, ignoring irrelevant information.
Change on Walking While Talking Test (WWT)
时间窗: 30 minutes (before and after the acute exercise intervention)
The WWT measures multitasking by comparing performance on a single motor task to the motor performance during a simultaneous motor + cognitive dual task.
次要结局
未报告次要终点
研究者
Carly Wender
Research Scientist
Kessler Foundation