Studies of apnoea in the newborn: Delivery of positive inflating pressure as early rescue

Not Applicable

Recruiting

• Conditions: Apnoea of prematurity; Respiratory - Other respiratory disorders / diseases; Reproductive Health and Childbirth - Complications of newborn

• Registration Number: ACTRN12619000740190
• Lead Sponsor: niversity of Tasmania

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-05-17
• Last Update Posted: 17 May 2021

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

Birth gestation <30 weeks
- Chronological age < /=4 months
- Supported with bubble CPAP
- Having frequent respiratory pauses 5+ seconds duration, resulting in episodes of hypoxia (SpO2 <85) and/or bradycardia (heart rate <100 bpm) at least twice per hour.
- Research team available to commence study
- Agreement of treating clinician that the infant is suitable for involvement in the study
- Signed parental consent

Exclusion Criteria

Change in mode of respiratory support, including use of non-triggered continuous non-invasive positive pressure ventilation (NIPPV) being contemplated in next 24 hours

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in frequency of apnoea lasting >5 seconds, expressed as events per hour , and quantified both on a per study and per infant basis will be compared between each epoch.<br><br>Events of apnoea will be determined and recorded via the Dräger Infinity monitor - a standard clinical monitoring device - and a modified Graseby MR10 respiratory monitor. [End of the study period for each infant - approximately 16 hours.]