NCT03085667已完成不适用
Impact of Implantation of an LAA Occluder on ANP and BNP Level and Quality of Life
University of Leipzig1 个研究点 分布在 1 个国家目标入组 25 人开始时间: 2011年1月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 25
- 试验地点
- 1
- 主要终点
- Change from baseline atrial natriuretic Peptide (ANP)
研究概览
简要总结
Closure of the LAA by several devices is a alternative therapy to oral anticoagulation in patients with Atrail fibrillation. Nothing is known about the acute influence of a device closure of the LAA on the secretion of ANB nad BNP hormones. Therefore aim of our study is to measure ANB and BNP levvels before and after Implantation of an LAA closure device.
详细描述
ANB and BNP levels are measured before, directly after and late after 24 h in central or periphereal venous blood from patients undergoing interventional LAA closure.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients undergoing LAA closure
排除标准
- 未提供
结局指标
主要结局
Change from baseline atrial natriuretic Peptide (ANP)
时间窗: 24 h post intervention
comparison of ANP level pre and post intervention
次要结局
未报告次要终点
研究者
Sven Möbius-Winkler
PI
University of Leipzig
研究点 (1)
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