CTRI/2024/12/078060尚未招募不适用
A Randomised and Comparative study of attenuation of hemodynamic responses to Laryngoscopy and Endotracheal Intubation during pre-induction with two different Intravenous doses of Labetalol.
Smt.Bhikiben Kanjibhai Shah Medical Institute and Research Centre1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2024年12月25日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- To study hemodynamic and respiratory responses during endotracheal and laryngeal intubation.
研究概览
简要总结
To study effect of two different doses of Inj. Labetalol iv in attenuating hemodynamic stress responses to laryngoscopy and endotracheal intubation in adult patients- A randomised and comparative study of attenuation of hemodynamic responses to laryngoscopy and endotracheal intubation during pre-induction with two different intravenous doses of Labetalol in adult patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients willing to sign written and informed consent.
- •Patients belonging to American Society of Anaesthesiologists(ASA) physical status I,II.
- •Patients posted for elective surgeries under general anaesthesia.
排除标准
- •Patients unwilling to participate in study.
- •Patients with Body Mass Index more than 30 mg/m
- •Patients with cardiovascular, cerebrovascular, hepatic and renal diseases.
- •Bradycardia, HR less than 70/min.
- •Arrhythmias.
- •Psychiatric patients.
- •Pregnancy and lactating women.
- •Patients belonging to the American Society of Anaesthesiologists (ASA) III and above.
- •Patients taking any type of medication for hypertension.
- •Patients allergic to the study drugs.
- •Patients with anticipated difficult airways.
结局指标
主要结局
To study hemodynamic and respiratory responses during endotracheal and laryngeal intubation.
时间窗: Preoperative | After test drug administration | During laryngoscopy and endotracheal intubation | At 1 min | At 3 min | At 5 min | At 7 min | At 10 min
次要结局
- To study any intra operative complications like bradycardia, hypotension, arrhythmias.(Hemodynamic parameters will be recorded every 2 minutes for 10 minutes after intubation.)
研究者
Isha Jhatakia
Smt.Bhikiben Kanjibhai Shah Medical Institute and Research Centre
研究点 (1)
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