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临床试验/NCT04688463
NCT04688463已完成不适用

Evaluation of Pressure Algometry in the Clinical Assessment of Acute Abdominal Pain in Children

University of Manitoba0 个研究点目标入组 427 人开始时间: 2000年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
427
主要终点
Appendicitis

研究概览

简要总结

In this retrospective observational case study, the investigators review the clinical experience with pressure-pain algometry in children with suspected appendicitis. The investigators hypothesized that algometry can discriminate children with appendicitis from children without appendicitis and aimed to determine the diagnostic accuracy of algometry, compared to ultrasound imaging and clinical assessment.

详细描述

As a retrospective cohort study, participants include all children referred with abdominal pain from January 2000 to June 2006 to one surgeon (R.P.) on the pediatric general surgery service at the Health Sciences Centre (HSC)-Children's Hospital in Winnipeg. The HSC-Children's Hospital is the only pediatric surgery centre within a radius of 600 km. All included participants have had acute abdominal pain ≤ 7 days, and suspected appendicitis based on standard history and physical exam. Standard appendicitis treatments were used: analgesia, antibiotics, operation. The Research Ethics Board of the University of Manitoba approved the study and reporting of the findings (H2003:104).

The investigators use standard clinical, laboratory, diagnostic imaging procedures for appendicitis diagnosis. The final diagnosis is defined by:

  • pathology report indicating transmural inflammation, or
  • from the surgeon's report when pathology was unavailable, or
  • by discharge diagnosis in non-operated patients.

Appendix rupture is defined by the presence of pus and full-thickness perforation of the appendix wall or abscess formation at operation or on pathology examination. The appendix condition is classified as normal, non-perforated or perforated; all other pathologies at operation are recorded. Treatments, complications and morbidity are tabulated.

Clinical Measures

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
2 Years 至 17 Years(Child)
性别
All
接受健康志愿者

入选标准

  • all children referred with abdominal pain from January 2000 to June 2006 to one surgeon on the pediatric general surgery service at the Health Sciences Centre (HSC)-Children's Hospital in Winnipeg.

排除标准

  • children with abdominal pain > 7 days
  • children with abdominal pain due to other surgical or medical conditions

结局指标

主要结局

Appendicitis

时间窗: within 1week

Diagnosis of appendicitis by pathology report if available.

Non-Appendicitis

时间窗: Within one (1) week

Diagnosis of non-appendicitis by observation only

Pressure-pain algometry

时间窗: Within one (1) week

Serial measurements taken before final management decision

次要结局

  • Complications following appendectomy(For one (1) month following operation or observation.)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Ray Postuma

Professor of Surgery - retired

University of Manitoba

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