Clinical Outcomes in patients with Esophageal Cancer treated with Definitive Chemoradiotherapy
- Conditions
- Health Condition 1: C159- Malignant neoplasm of esophagus, unspecified
- Registration Number
- CTRI/2021/03/032343
- Lead Sponsor
- one
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1. Histologically confirmed non-recurrent non-metastatic squamous cell carcinoma or adenocarcinoma of esophagus or gastroesophageal junction (GEJ).
2. Patients must be considered as having inoperable/unresectable tumor, considered to be unfit for surgery and/or are unwilling for surgery.
3. ECOG performance status less than or equal to 2.
4. Adequate baseline bone marrow, liver and renal functions as determined by routine standard-of-care tests.
5. Patients being treated using VMAT technique.
6. Willingness to participate in the study and provides a voluntary informed consent.
1. Metastatic disease at presentation.
2. History of prior mediastinal/thoracic malignancy or condition that warranted irradiation or chemotherapy.
3. Patients with tracheoesophageal fistula/bronchoesophageal fistula.
4. Patients with active second malignancy.
5. Uncontrolled co-morbidities that would hamper the patientsâ?? adherence to treatment.
6. Known contraindications to use of concurrent chemotherapy (E.g.: impaired renal/hematological function, known hypersensitivity, etc.)
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method