An Epidemiological Study of Acute Coronary Syndromes in The Greek Population. The TARGET Study

Completed

• Conditions: Acute Coronary Syndromes

• Registration Number: NCT01061086
• Lead Sponsor: AstraZeneca

Brief Summary

This is a multicenter, 2-phase observational study of acute coronary syndromes (ACS) in Greece, designed to provide real world data on the risk factors of patients presenting to a hospital emergency department with an index event, as well as to depict the current management practices and outcomes of these clinical conditions in Greece.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-01
• Study First Submitted: 2010-02-01
• Study First Submitted QC: 2010-02-01
• Study First Posted: 2010-02-02
• Primary Completion: 2010-06
• Study Completion: 2011-02
• Status Verified: 2011-12
• Last Update Submitted: 2011-12-20
• Last Update Posted: 2011-12-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 418

Inclusion Criteria

• Diagnosis of an ACS (STEMI, NSTEMI, UA).
• Informed Consent

Exclusion Criteria

• Involvement in the planning and conduct of the study (applies to both AstraZeneca staff and staff at the study sites).
• Participation in other clinical study in period between the index event and 6- month follow-up assessment with the exception of registering in registries or surveys not influencing the management of the ACS.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To evaluate the proportion of patients who are on target for LDL-C according to the 2004-updated NCEP ATPIII guidelines as calculated within the first 24-hours of hospital admission for an ACS.	first visit - 1st day (cross-sectional part)
To estimate the proportion of patients enrolled in the cross-sectional part of the study that experiences a Major Adverse Cardiovascular Event (MACE) within a 6-month follow-up period.	follow up visit - 6th month (prospective part)

Secondary Outcome Measures

Name	Time	Method
To estimate the proportion of patients admitted to the hospital with STEMI, NSTEMI and unstable angina.	first visit - 1st day (cross-sectional part)
To estimate the "pain-to-door-time" throughout different regions in Greece.	first visit - 1st day (cross-sectional part)
To estimate the time to first MACE and to estimate CV, non-CV and all cause mortality within the 6-month period following the index ACS event.	follow up visit - 6th month (prospective part)

Trial Locations

Locations (1)

Research Site; 🇬🇷 Chios, Greece