跳至主要内容
临床试验/NCT05628051
NCT05628051已完成不适用

Effect of Carotid Corrected Flow Time Combined With Perioperative Fluid Therapy on Preventing Hypotension After General Anesthesia Induction in Elderly Patients

Fujian Medical University Union Hospital1 个研究点 分布在 1 个国家目标入组 177 人开始时间: 2022年6月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
177
试验地点
1
主要终点
Carotid artery corrected flow time (FTc)

研究概览

简要总结

The number of elderly patients undergoing elective surgery has been growing in recent years. Elderly patients often have a variety of underlying diseases, including hypertension, coronary heart disease, diabetes, arteriosclerosis, etc., which increase the risk. When the elderly receive general anesthesia, hypotension often occurs after anesthesia induction. Once hypotension occurs, it may lead to myocardial ischemia, myocardial infarction, stroke and other serious complications. Therefore, in clinical anesthesia, a simple, quick and accurate prediction method is needed to evaluate and predict the risk of hypotension in elderly patients after induction, so that appropriate intervention measures can be taken in advance to reduce the incidence of hypotension in elderly patients after induction, thus reducing the occurrence of related complications and ensuring the safety of anesthesia and surgery.Carotid Artery Corrected Flow Time(FTc) is a recently developed volumetric predictor, which refers to the time between the the onset of systolic flow until the closure of the aortic valve. It is related to cardiac preload and can reflect cardiac output to a certain extent. It is considered as a reliable indicator for evaluating volume status and volumetric reactivity. Therefore, this study assessed the effect of FTc combined with perioperative fluid therapy on preventing hypotension after general anesthesia induction in elderly patients.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
65 Years 至 85 Years(Older Adult)
性别
All
接受健康志愿者

入选标准

  • patients who received elective surgery under general anesthesia, aged 65-85 years old, gender unlimited, ASAI-II

排除标准

  • uncontrolled hypertension
  • unstable angina pectoris
  • history of myocardial infarction
  • after heart stent implantation
  • severe arrhythmia:Atrial fibrillation、Ventricular premature beat, frequent atrial premature beat, other non-sinus rhythm
  • pacemaker implants
  • cardiomyopathy
  • a left ventricular ejection fraction of < 40%
  • history of neck trauma and surgery

结局指标

主要结局

Carotid artery corrected flow time (FTc)

时间窗: 5 minutes before induction of general anesthesia

the area under the receiver operating characteristics curve of corrected flow time in carotid artery measured by ultrasonography to predict hypotension after anesthetic induction

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

Loading locations...

相似试验

Carotid Artery Corrected Flow Time as a Predictor of... | 临床试验