Effect of Carotid Corrected Flow Time Combined With Perioperative Fluid Therapy on Preventing Hypotension After General Anesthesia Induction in Elderly Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 177
- 试验地点
- 1
- 主要终点
- Carotid artery corrected flow time (FTc)
研究概览
简要总结
The number of elderly patients undergoing elective surgery has been growing in recent years. Elderly patients often have a variety of underlying diseases, including hypertension, coronary heart disease, diabetes, arteriosclerosis, etc., which increase the risk. When the elderly receive general anesthesia, hypotension often occurs after anesthesia induction. Once hypotension occurs, it may lead to myocardial ischemia, myocardial infarction, stroke and other serious complications. Therefore, in clinical anesthesia, a simple, quick and accurate prediction method is needed to evaluate and predict the risk of hypotension in elderly patients after induction, so that appropriate intervention measures can be taken in advance to reduce the incidence of hypotension in elderly patients after induction, thus reducing the occurrence of related complications and ensuring the safety of anesthesia and surgery.Carotid Artery Corrected Flow Time(FTc) is a recently developed volumetric predictor, which refers to the time between the the onset of systolic flow until the closure of the aortic valve. It is related to cardiac preload and can reflect cardiac output to a certain extent. It is considered as a reliable indicator for evaluating volume status and volumetric reactivity. Therefore, this study assessed the effect of FTc combined with perioperative fluid therapy on preventing hypotension after general anesthesia induction in elderly patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 65 Years 至 85 Years(Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients who received elective surgery under general anesthesia, aged 65-85 years old, gender unlimited, ASAI-II
排除标准
- •uncontrolled hypertension
- •unstable angina pectoris
- •history of myocardial infarction
- •after heart stent implantation
- •severe arrhythmia:Atrial fibrillation、Ventricular premature beat, frequent atrial premature beat, other non-sinus rhythm
- •pacemaker implants
- •cardiomyopathy
- •a left ventricular ejection fraction of < 40%
- •history of neck trauma and surgery
结局指标
主要结局
Carotid artery corrected flow time (FTc)
时间窗: 5 minutes before induction of general anesthesia
the area under the receiver operating characteristics curve of corrected flow time in carotid artery measured by ultrasonography to predict hypotension after anesthetic induction
次要结局
未报告次要终点
