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Clinical Trials/NCT01936298
NCT01936298
Completed
Not Applicable

Robot-assisted Rehabilitation of Hand by Paralysis of the Upper Limb After Stroke

Chiara Mulé1 site in 1 country35 target enrollmentSeptember 2013
ConditionsStroke

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Stroke
Sponsor
Chiara Mulé
Enrollment
35
Locations
1
Primary Endpoint
Change from Baseline of Perimeter edema
Status
Completed
Last Updated
12 years ago

Overview

Brief Summary

The investigators evaluate the effectiveness of the application of continuous passive motion device for hand rehabilitation in two classes of patients: with a residual active motion and without a residual active motion.

Detailed Description

We will conduct a double blind clinical trial. A sample size calculation were performed to determine the necessary number of subjects needed for this study and was based upon the results of a previous pilot study. All patients had functional impairments of their upper extremities after the stroke. We hypothesized that the hand-rehabilitation oriented with robotics assistance, would improve edema by paralysis of the upper limb even in patient without sensory pathway recovery.

Registry
clinicaltrials.gov
Start Date
September 2013
End Date
October 2013
Last Updated
12 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Chiara Mulé
Responsible Party
Sponsor Investigator
Principal Investigator

Chiara Mulé

Physiatrist Physician

Habilita, Ospedale di Sarnico

Eligibility Criteria

Inclusion Criteria

  • a history of acute phase of stroke (less than 12 months post onset),
  • first stroke episode,
  • no history of peripheral nerve injury or musculoskeletal disease in the affected upper extremity,
  • no contracture of the affected wrist or fingers (Modified Ashworth\<3),
  • no history of any invasive procedure (Botulinum toxin type A) for the treatment of spasticity for at least 6 months before the start of this study,
  • for P-ROM patients, the absence of active hand movements,
  • for the A-ROM patients, the presence of active hand movements.

Exclusion Criteria

  • unstable medical disorders,
  • active Complex Regional Pain Syndrome (CRPS),
  • severe spatial neglect,
  • cognitive problems.

Outcomes

Primary Outcomes

Change from Baseline of Perimeter edema

Time Frame: 1 day after the treatment

Secondary Outcomes

  • Change from Baseline of Visual analogue scale (VAS)(1 day after the treatment)
  • Change from Baseline of Modified Ashworth Scale for Grading Spasticity (MAS)(1 day after the treatment)
  • Change from Baseline of Range Of Motion (ROM)(1 day after the treatment)
  • Clinical Global Impression (CGI)(1 day after the treatment)

Study Sites (1)

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