Study of a New Protease Inhibitor, BMS-232632, in Combination With Other Anti-HIV Drugs
- Conditions
- HIV Infections
- Registration Number
- NCT00002240
- Lead Sponsor
- Bristol-Myers Squibb
- Brief Summary
The purpose of this study is to evaluate a new protease inhibitor known as BMS-232632. This drug will be given in combination with 2 other anti-HIV drugs (stavudine and didanosine). The effectiveness of BMS-232632 against HIV infection will be compared to that of nelfinavir, a protease inhibitor that is already commonly prescribed.
- Detailed Description
Patients are randomized to receive one of two drug regimens: BMS-232632, ddI, and d4T or NFV, ddI, and d4T. Three different doses of BMS-232632 are used in this study. Randomization is stratified for HIV RNA level (less than 30,000 copies/ml versus 30,000 or greater copies/ml). Patients remain on their drug regimen for 48 weeks.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- Not specified
Not provided
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (17)
AIDS Research Consortium of Atlanta
🇺🇸Atlanta, Georgia, United States
Albany Med College
🇺🇸Albany, New York, United States
Clinsites / Sorra Research Ctr
🇺🇸Birmingham, Alabama, United States
Beth Israel Med Ctr
🇺🇸New York, New York, United States
Washington Univ School of Medicine
🇺🇸St Louis, Missouri, United States
Rush Presbyterian - Saint Luke's Med Ctr
🇺🇸Chicago, Illinois, United States
Univ of Texas Southwestern Med Ctr of Dallas
🇺🇸Dallas, Texas, United States
Columbia Presbyterian Med Ctr
🇺🇸New York, New York, United States
Case Western Reserve Univ
🇺🇸Cleveland, Ohio, United States
ViRx / Dupont Circle Physicians Group
🇺🇸Washington, District of Columbia, United States
UCSD Treatment Ctr
🇺🇸San Diego, California, United States
Oak Lawn Physicians Group
🇺🇸Dallas, Texas, United States
Univ TX Galveston Med Branch
🇺🇸Galveston, Texas, United States
Ottawa General Hospital
🇨🇦Ottawa, Ontario, Canada
Univ of Alabama at Birmingham
🇺🇸Birmingham, Alabama, United States
UCSF - San Francisco Gen Hosp
🇺🇸San Francisco, California, United States
Univ of Colorado / Health Science Ctr
🇺🇸Denver, Colorado, United States