MedPath

The Effectiveness of Using a Clinical Support Tool in Managing Adolescents With Non-Traumatic Knee Pain

Not Applicable
Active, not recruiting
Conditions
Knee Pain Chronic
Interventions
Other: Usual practice
Other: Using the MAP-Knee Tool
Registration Number
NCT05791513
Lead Sponsor
Aalborg University
Brief Summary

The aim of the stepped-wedge cluster randomised trial is to investigate the effectiveness of using a clinical support tool (The MAP-Knee Tool) in managing adolescents aged 10-19 years with non-traumatic knee pain compared to not using the tool. Six participating hospitals will start to use the tool within 4, 6, or 8 months after recruitment start in a randomised order. We will investigate if using the tool is superior in terms of reducing symptoms compared to not using the tool.

Detailed Description

The trial will be designed as a stepped-wedge cluster randomised superiority trial to be conducted across 6 hospital departments across Denmark. Any orthopaedic or similar hospital department in Denmark to which adolescents suffering from non-traumatic knee pain may be referred is eligible for participation. Any medical doctor or physiotherapist employed at either of the study sites who regularly see adolescents with non-traumatic knee pain will be eligible to participate in the trial.

Before crossover occurs at the study site, the adolescents will be treated as usual which is at the discretion of the treating clinician. Based on our current research on the usual care pathway, this will be heterogenous and include advice to wait and see, imaging (most often MRI and x-ray), or a rehabilitation plan for the municipality. After crossing over to using the MAP-Knee Tool, the treating clinician will use the MAP-Knee Tool together with the adolescent. The tool was designed to support the entire consultation from diagnosing the condition (patellofemoral pain, Osgood-Schlatter, Sinding-Larsson-Johansson, growth pain, patellar tendinopathy, or iliotibial band syndrome) to deciding on future management. The MAP-Knee Tool includes four separate components: 1) a tool for diagnosing the most common types of non-traumatic knee pain (SMILE), 2) credible explanations of the aetiology and pathogenesis specific to the diagnosis based on multiple methods with an iterative design, 3) a presentation of prognostic factors based on an individual participant data meta-analysis, and 4) an option grid that presents the users of the tool with pros and cons of commonly used management options based on a systematic literature search of systematic and narrative reviews within non-traumatic adolescent knee pain. An overarching focus of all components was to support shared decision-making and base decisions on all three pillars of evidence-based medicine: patient values, clinical expertise, and relevant research. Therefore, the tool should not provide the users with definitive answers simply based on available evidence. After the initial prototype of the tool including all four components had been made, the investigators performed end-user testing using think-aloud sessions with adolescents suffering from non-traumatic knee pain, adolescents with no history of knee pain, and medical doctors.

Recruitment & Eligibility

Status
ACTIVE_NOT_RECRUITING
Sex
All
Target Recruitment
110
Inclusion Criteria
  • Having been referred to a hospital due to non-traumatic knee pain
  • Age between 10 and 19 years
Exclusion Criteria
  • Knee pain with a traumatic origin
  • Lack of ability to cooperate

Study & Design

Study Type
INTERVENTIONAL
Study Design
SEQUENTIAL
Arm && Interventions
GroupInterventionDescription
Not using the MAP-Knee ToolUsual practiceThe treating clinician will not use the MAP-Knee Tool in the consultation and will conduct the consultation as per usual practice.
Using the MAP-Knee ToolUsing the MAP-Knee ToolThe treating clinician will use the MAP-Knee Tool together with the adolescent. The tool includes four separate components: 1) a tool for diagnosing the most common types of non-traumatic knee pain (SMILE), 2) credible explanations of the aetiology and pathogenesis specific to the diagnosis based on multiple methods with an iterative design, 3) a presentation of prognostic factors based on an individual participant data meta-analysis(19), and 4) an option grid that presents the users of the tool with pros and cons of commonly used management options based on a systematic literature search of systematic and narrative reviews within non-traumatic adolescent knee pain. An overarching focus of all components was to support shared decision-making and base decisions on all three pillars of evidence-based medicine: patient values, clinical expertise, and relevant research. Therefore, the tool should not provide the users with definitive answers simply based on available evidence.
Primary Outcome Measures
NameTimeMethod
KOOS-Child Pain subscaleDuring baseline and at the 12-week and 52-week follow-ups

KOOS-Child consists of 39 items divided into five subscales (Pain, Symptoms, Activities of Daily Living, Sport/Recreation, and Quality of Life) that each range from 0 to 100 with 100 being optimum. This questionnaire has been found to have good psychometric properties and is recommended for children and adolescents suffering from knee disorders.

Secondary Outcome Measures
NameTimeMethod
KOOS-Child Activities of daily living subscaleDuring baseline and at the 12-week and 52-week follow-ups

KOOS-Child consists of 39 items divided into five subscales (Pain, Symptoms, Activities of Daily Living, Sport/Recreation, and Quality of Life) that each range from 0 to 100 with 100 being optimum. This questionnaire has been found to have good psychometric properties and is recommended for children and adolescents suffering from knee disorders.

KOOS-Child Quality of Life subscaleDuring baseline and at the 12-week and 52-week follow-ups

KOOS-Child consists of 39 items divided into five subscales (Pain, Symptoms, Activities of Daily Living, Sport/Recreation, and Quality of Life) that each range from 0 to 100 with 100 being optimum. This questionnaire has been found to have good psychometric properties and is recommended for children and adolescents suffering from knee disorders.

EQ-5D-YDuring baseline and at the 12-week and 52-week follow-ups

Health-related quality of life will be estimated by the EQ-5D-Youth questionnaire which is an adapted version of the EQ-5D used in an adult population, yet, it still consists of the same five subscales which are mobility, self-care, usual activities, pain and discomfort, and anxiety and depression.

Global Rating of ChangeAt the 12-week and 52-week follow-ups

This will be used to measure the participants' self-reported recovery on a 7-point Likert scale ranging from "much improved" to "much worse". Participants are categorised as improved if they rate themselves as "much improved" or "improved" (category 6-7) and categorised as not improved if they rate themselves from "slightly improved" to "much worse" (category 1-5).

Sports participationDuring baseline and at the 12-week and 52-week follow-ups

Change in sports participation will be explored using a questionnaire in which participants are asked about whether they have participated in leisure sports activities, type of sports activities and weekly frequency.

KOOS-Child Sport/recreation subscaleDuring baseline and at the 12-week and 52-week follow-ups

KOOS-Child consists of 39 items divided into five subscales (Pain, Symptoms, Activities of Daily Living, Sport/Recreation, and Quality of Life) that each range from 0 to 100 with 100 being optimum. This questionnaire has been found to have good psychometric properties and is recommended for children and adolescents suffering from knee disorders.

International Physical Activity Questionnaire short version (IPAQ).During baseline and at the 12-week and 52-week follow-ups

The IPAQ is the most used questionnaire for measuring physical activity and consists of 9 items that provide information on the time spent performing vigorous and moderate activities, the time spent walking, and time spent sedentary during the past week. The IPAQ gives an estimate of the total weekly physical activity measured in MET-minutes per week and total minutes spent sitting.

KOOS-Child Symptoms subscaleDuring baseline and at the 12-week and 52-week follow-ups

KOOS-Child consists of 39 items divided into five subscales (Pain, Symptoms, Activities of Daily Living, Sport/Recreation, and Quality of Life) that each range from 0 to 100 with 100 being optimum. This questionnaire has been found to have good psychometric properties and is recommended for children and adolescents suffering from knee disorders.

Trial Locations

Locations (6)

Aalborg Universitetshospital

🇩🇰

Aalborg, Denmark

Amager-Hvidovre Hospital

🇩🇰

København, Denmark

Næstved Sygehus

🇩🇰

Næstved, Denmark

Bispebjerg Hospital

🇩🇰

København, Denmark

Sportsmedicinsk Center

🇩🇰

Frederikshavn, Denmark

Vejle Sygehus

🇩🇰

Vejle, Denmark

© Copyright 2025. All Rights Reserved by MedPath