Linking Hospitalized Injection Drug Users to Buprenorphine
- Conditions
- Opiate Dependence
- Interventions
- Behavioral: Linkage
- Registration Number
- NCT00987961
- Lead Sponsor
- Butler Hospital
- Brief Summary
This study tests whether starting Suboxone (buprenorphine) during a medical hospitalization, and then providing an appointment (a "link") for after discharge to maintenance buprenorphine in an outpatient setting will reduce HIV risk behavior in individuals who inject opioids.
- Detailed Description
In this randomized controlled trial, medically hospitalized opioid dependent patients will be assigned to a "treatment as usual" group, where they will receive a detox regiment of Suboxone during their hospital stay, or a "linkage" group, where they receive a maintenance course of Suboxone during their hospital stay, and appointment post-discharge with an outpatient Suboxone clinic/provider and a Suboxone prescription to use between discharge and this appointment. Study interviews are completed at baseline, and 1, 3- and 6-months post-baseline. Primary outcomes are opioid use and HIV risk behavior.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 147
- 18 years of age or older
- Current opioid injector, at least weekly in the past month
- Current opioid dependence, SCID confirmed
- Currently receiving an inpatient buprenorphine detoxification protocol.
- Patients unable to be interviewed due to acute illness or cognitive impairment
- In police custody, expecting incarceration
- Persons who cannot provide two contact persons (including shelters, parole officers, etc.) to verify location
- Not able to complete assessments in English
- Enrolled in a methadone maintenance program
- Plans to leave the area within the next 6 months.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Linkage Linkage Participants in this arm will receive a maintenance schedule of Suboxone during their hospital stay, and an appointment with an outpatient Suboxone provider for after their discharge.
- Primary Outcome Measures
Name Time Method opioid use baseline, 1-month, 3-months, 6-months HIV risk behavior baseline, 1-month, 3-months, 6-months
- Secondary Outcome Measures
Name Time Method reduction in injection-related medical conditions baseline, 1-month, 3-months, 6-months reduction in emergency department and hospital utilization baseline, 1-month, 3-months, 6-months
Trial Locations
- Locations (1)
Boston Medical Center
🇺🇸Boston, Massachusetts, United States