To measure effect of low dose aspirin in patient undergoing routine dental extraction such as increase bleeding or not.
- Conditions
- Health Condition 1: null- patients withcardiovascular or peripheral venous disease who are on low dose aspirin ranging from 75-150mg requiring routine dental extractions.
- Registration Number
- CTRI/2016/12/007550
- Lead Sponsor
- Bharati Vidyapeeth Deemed University Dental College And HospitalPune
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 100
1.Patient on long term low dose single anti-platelet therapy aspirin (75 to 150mg).
2.Patients with PT- INR less than 1.5.
3.Patients between 30-60 years of age.
4.Patients without any bleeding disorders.
5.Not allergic to the drugs or anesthetic agent being used.
6.Patients willing to participate in study.
7.Patient with fitness obtained from physician to undergo exodontia.
1)Patients on aspirin therapy >150mg/day.
2) Patients INR >3.5.
3)Pregnant or lactating women.
4)Patients with hepatic, renal diseases or epilepsy or with a clinical history of debilitating respiratory diseases.
6)Patients with bleeding or clotting disorders.
7)Patients belonging to ASA Grade III, IV, V.
8)Procedure under General Anesthesia or Conscious sedation.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Perioperative blood loss was measured for each extraction by swab weighing method both in test group and control group.Number of gauze used and time of bleeding (early, immediate or late) postoperatively.The patients were checked after 24 hours, 48 hours,72 hours and 1 week, and bleeding complaints were recorded.Use of local haemostatic agrnts like sutures, gel foam, tranexamic acid, botroclot, electrocautery were also assessed at different time intervals after exodontia.Timepoint: Bleeding is measured quantatively by gauze weighing method intraopeartively and qualitatively after interval of 30mins,24hrs, 48 hrs,72 hrs and 1week postoperatively.
- Secondary Outcome Measures
Name Time Method Postoperative bleeding if any after 1 week and need for fresh frozen plasma transfusion if bleeding continues after 1week.Timepoint: 1week