The Effectiveness of tDCS on Internet Game Addiction

Phase 2

Completed

• Conditions: Internet Gaming Disorder; Addiction
• Interventions: Device: tDCS with sham stimulation; Device: tDCS with real stimulation

• Registration Number: NCT03347643
• Lead Sponsor: Seoul National University Hospital

Brief Summary

In this study, the investigators aimed to investigate the effect of transcranial direct current stimulation (tDCS) on clinical status of Internet game addiction. The clinical status of Internet game addiction includes severity of addiction symptom, subjective craving for gaming, response inhibition and cue reactivity. The investigators hypothesized that real stimulation with tDCS on the dorsolateral prefrontal cortex will have higher effectiveness on severity of addiction symptom, subjective craving for gaming, response inhibition and cue reactivity rather than sham stimulation with tDCS.

Detailed Description

Not available

Study Timeline

• Study Start: 2017-09-22
• Study First Submitted: 2017-11-13
• Study First Submitted QC: 2017-11-15
• Study First Posted: 2017-11-20
• Primary Completion: 2019-09-01
• Study Completion: 2019-10-08
• Status Verified: 2020-03
• Last Update Submitted: 2020-03-23
• Last Update Posted: 2020-03-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 31

Inclusion Criteria

• Diagnosis of Internet gaming disorder based on diagnostic criteria of Diagnostic and Statistical Manual of Mental Disorders (DSM)-5.

Exclusion Criteria

• History of seizure
• History of significant head injury
• Mental retardation
• Schizophrenia
• History of stroke

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
tDCS with sham stimulation	tDCS with sham stimulation	A total of 25 patients will be allocated into sham comparator with sham stimulation with tDCS.
tDCS with real stimulation	tDCS with real stimulation	A total of 25 patients will be allocated into active comparator with real stimulation with tDCS.

Primary Outcome Measures

Name	Time	Method
Young Internet Addiction Test (Y-IAT)	25 week	The Y-IAT is rated on a five-point scale. Total scores for all 20 items range from 20 to 100.

Secondary Outcome Measures

Name	Time	Method
Direction error and successful stop ratio in the Stop signal task	baseline, 5 weeks, 25 weeks	The stop signal task is a neurocognitive task for assessing response inhibition.
Barratt impulsiveness scale-11	baseline, 5 weeks, 25 weeks	Barratt impulsiveness scale-11 is a self-report questionnaire consisting of 30 items. Each question has a 4-point scale ranging from 1 (rarely/never) to 4 (almost always/always). This scale scores three subscales: attentional impulsiveness, motor impulsiveness, and nonplanning impulsiveness. The total score ranges from 30 to 120 and higher scores indicate greater impulsivity.
Anti-saccade error rate in the attentional bias task	baseline, 5 weeks, 25 weeks	The attentional bias task is measured by anti-saccade task using eye-tracking analysis for assessing attentional bias on Internet gaming stimuli.
Late positive potential in the cue reactivity event-related potential	baseline, 5 weeks, 25 weeks	Event-related potential measures with cue reactivity task
Visual analogue scale	baseline, 1 week, 5 weeks, 25 weeks	Subjective craving for Internet gaming ranging from 0 to 10. Higher score represents higher craving for gaming.

Trial Locations

Locations (1)

SMG-SNU Boramae Medical Center; 🇰🇷 Seoul, Korea, Republic of