Randomized Double-blind Clinical Trial to Evaluate the Effectiveness of Transcranial Direct Current Stimulation (tDCS) on Internet Game Addiction
Trial Snapshot
- Phase
- Phase 2
- Status
- Completed
- Enrollment
- 31
- Locations
- 1
- Primary Endpoint
- Young Internet Addiction Test (Y-IAT)
Study Overview
Brief Summary
In this study, the investigators aimed to investigate the effect of transcranial direct current stimulation (tDCS) on clinical status of Internet game addiction. The clinical status of Internet game addiction includes severity of addiction symptom, subjective craving for gaming, response inhibition and cue reactivity. The investigators hypothesized that real stimulation with tDCS on the dorsolateral prefrontal cortex will have higher effectiveness on severity of addiction symptom, subjective craving for gaming, response inhibition and cue reactivity rather than sham stimulation with tDCS.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Double (Participant, Investigator)
Eligibility Criteria
- Ages
- 18 Years to 50 Years (Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Diagnosis of Internet gaming disorder based on diagnostic criteria of Diagnostic and Statistical Manual of Mental Disorders (DSM)-5.
Exclusion Criteria
- •History of seizure
- •History of significant head injury
- •Mental retardation
- •Schizophrenia
- •History of stroke
Arms & Interventions
tDCS with real stimulation
A total of 25 patients will be allocated into active comparator with real stimulation with tDCS.
Intervention: tDCS with real stimulation (Device)
tDCS with sham stimulation
A total of 25 patients will be allocated into sham comparator with sham stimulation with tDCS.
Intervention: tDCS with sham stimulation (Device)
Outcomes
Primary Outcomes
Young Internet Addiction Test (Y-IAT)
Time Frame: 25 week
The Y-IAT is rated on a five-point scale. Total scores for all 20 items range from 20 to 100.
Young Internet Addiction Test (Y-IAT)
Time Frame: baseline
The Y-IAT is rated on a five-point scale. Total scores for all 20 items range from 20 to 100.
Young Internet Addiction Test (Y-IAT)
Time Frame: 1 week
The Y-IAT is rated on a five-point scale. Total scores for all 20 items range from 20 to 100.
Young Internet Addiction Test (Y-IAT)
Time Frame: 5 week
The Y-IAT is rated on a five-point scale. Total scores for all 20 items range from 20 to 100.
Secondary Outcomes
- Direction error and successful stop ratio in the Stop signal task(baseline, 5 weeks, 25 weeks)
- Barratt impulsiveness scale-11(baseline, 5 weeks, 25 weeks)
- Anti-saccade error rate in the attentional bias task(baseline, 5 weeks, 25 weeks)
- Late positive potential in the cue reactivity event-related potential(baseline, 5 weeks, 25 weeks)
- Visual analogue scale(baseline, 1 week, 5 weeks, 25 weeks)
Investigators
Jung-Seok Choi
Clinical associate professor
Seoul National University Hospital