Assessing the Impact of Isokinetic Muscular Strengthening in Eccentric Mode in the Medical Treatment of Knee Osteoarthritis.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 40
- 试验地点
- 2
- 主要终点
- Difference of peak torque of quadriceps
研究概览
简要总结
Knee osteoarthritis (O.A. from now on) is associated to muscular weakness of inferior limbs, especially the quadriceps; leading to disease progression. Advantages of muscular strength training for the treatment of this kind of O.A. is now well established. In this therapeutic field, isokinetic exercises seem to have a better efficiency than other, more frequently used, kinds of exercises such as isometric or isotonic exercises.
Functional impairment caused by knee O.A. is mainly affecting walking. Walking induces muscles to work in eccentric mode.
The hypothesis of this study is that muscular strengthening using isokinetic exercises in eccentric mode would have a more important benefit than isokinetic exercises in concentric mode. Such an hypothesis, if verified, could lead to a better management of rehabilitative knee exercises in the treatment of knee O.A.
详细描述
Knee osteoarthritis (O.A. from now on) is associated to muscular weakness of inferior limbs, especially the quadriceps; leading to disease progression. Advantages of muscular strength training for the treatment of this kind of O.A. is now well established. In this therapeutic field, isokinetic exercises seem to have a better efficiency than other, more frequently used, kinds of exercises such as isometric or isotonic exercises.
Functional impairment caused by knee O.A. is mainly affecting walking. Walking induces muscles to work in eccentric mode.
The hypothesis of this study is that muscular strengthening using isokinetic exercises in eccentric mode would have a more important benefit than isokinetic exercises in concentric mode. Such an hypothesis, if verified, could lead to a better management of rehabilitative knee exercises in the treatment of knee O.A.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 40 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient male or female, age ranging from 40 to 70 years old
- •Patient suffering from one-sided knee O.A. regarding criteria of the American College of Rheumatology (A.C.R.), with radiologic score ranging from 2 to 3 according to the Kellgren & Lawrence classification.
- •Patient receiving medical support
- •Patient that did not receive any infiltration on knee within two months before randomisation.
- •Patient free from any disease that could be a contraindication to the study treatment
- •Patient able to understand the protocol and willing to comply with its rules.
- •Patient willing to give consent.
- •Patient affiliated to the french social secu
排除标准
- •Patient carrying prosthesis.
- •Patient suffering from inflammatory arthritis, or flare of arthritis.
- •Patient suffering from symptomatic patellofemoral osteoarthritis.
- •Patient suffering from cardio-vascular or pneumologic disease that could a contraindication to the study treatment.
- •Patient suffering from any pathology that could cause muscular weakness (myopathy, neuropathy, hemiplegia...)
研究组 & 干预措施
isokinetic exercises in concentric mode
干预措施: Exercise in eccentric or concentric mode (Other)
isokinetic exercises in eccentric mode
干预措施: Exercise in eccentric or concentric mode (Other)
结局指标
主要结局
Difference of peak torque of quadriceps
时间窗: 6 months after treatment start
次要结局
- Posture parameters (posturography)(at day 1, 6 weeks, and 6 months)
- Knee pain (via analogic visual scales)(at day 1, 6 weeks, and 6 months)
- WOMAC Scores(at day 1, 6 weeks, and 6 months)
- Knee range of motion (goniometer)(at day 1, 6 weeks, and 6 months)
- Walk speed (50 meters and 200 meters)(at day 1, 6 weeks, and 6 months :)
- Knee perimeter(at day 1, 6 weeks, and 6 months)
- Kellgren & Lawrence scores(at day 1, 6 weeks, and 6 months)