Protein Timing, Lean Mass, Strength and Functional Capacity Gains in Postmenopausal Women

Not Applicable

Completed

• Conditions: Sarcopenia
• Interventions: Dietary Supplement: Protein and carbohydrate supplementation

• Registration Number: NCT03372876
• Lead Sponsor: Federal University of Uberlandia

Brief Summary

This study evaluated the effect of protein intake immediately after resistance exercise on lean mass, strength, and functional capacity gains in postmenopausal women. Participants were randomly assigned to protein-carbohydrate group (PC) (n=17), that ingested 30 g of whey protein immediately after exercise and 30 g of maltodextrin in the afternoon; and to carbohydrate-protein group (CP) (n=17), that ingested 30 g of maltodextrin immediately after exercise and 30 g of whey protein in the afternoon. Both groups performed the same resistance training protocol in the morning.

Detailed Description

Both groups performed the same training protocol, differing only the time of protein or carbohydrate supplementation. The dietary assessment was made through the 24-hour food recall, being conducted at the beginning, middle and end of the intervention. Resistance exercises for upper and lower limbs will be performed, at 70% of one repetition maximum. One maximum repetition (1-RM), handgrip strength and 1-mile walk were performed.

Study Timeline

• Study Start: 2017-05-08
• Primary Completion: 2017-10-04
• Study Completion: 2017-10-11
• Status Verified: 2017-12
• Study First Submitted: 2017-12-10
• Study First Submitted QC: 2017-12-10
• Last Update Submitted: 2017-12-13
• Study First Posted: 2017-12-14
• Last Update Posted: 2017-12-15

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 34

Inclusion Criteria

• Women in the postmenopausal period (menopausal for at least one year, confirmed by laboratory diagnostic tests menopause - LH and high FSH and estradiol decreased);
• Healthy;
• Who agree to participate and sign the consent term.

Exclusion Criteria

• The one who does not provide the necessary information for the development of the study;
• Present orthopedic limitations;
• Patients with previously diagnosed and treatment of diseases such as type II diabetes mellitus, hypertension and cardiovascular disease.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Protein-carbohydrate (PC) (protein intake after exercise)	Protein and carbohydrate supplementation	ingested 30 g of whey protein immediately after exercise and 30 g of maltodextrin in the afternoon. The resistance exercise was performed equally by both groups.
Carbohydrate-protein (CP) (protein intake far to exercise)	Protein and carbohydrate supplementation	ingested 30 g of maltodextrin immediately after exercise and 30 g of whey protein in the afternoon. The resistance exercise was performed equally by both groups.

Primary Outcome Measures

Name	Time	Method
Changes in the lean mass of postmenopausal women practicing resistance exercise	Before and immediately after the intervention (initial moment and 8 weeks after start of the intervention)

Secondary Outcome Measures

Name	Time	Method
Changes on strength of postmenopausal women practicing resistance exercise	Before and immediately after the intervention (initial moment and 8 weeks after start of the intervention)
Changes on functional capacity of postmenopausal women practicing resistance exercise	Before and immediately after the intervention (initial moment and 8 weeks after start of the intervention)

Trial Locations

Locations (1)

Erick P. de Oliveira; 🇧🇷 Uberlândia, Minas Gerais, Brazil