ECG Versus Ultrasound-guided Positioning of the Peripherally Inserted Central Catheter (PICC) Tip

Not Applicable

Completed

• Conditions: Infection; Malnutrition; Cancer
• Interventions: Device: ECG-guided insertion of PICC; Device: ULTRASOUND-guided insertion of PICC

• Registration Number: NCT02467049
• Lead Sponsor: Universitair Ziekenhuis Brussel

Brief Summary

In the prevention of thrombosis related to catheter placement it is important to have a right position of the catheter tip. Therefor we want to assess which technique is the most successful in the placing of a PICC.

Detailed Description

This is a randomised prospective single blinded study. All adult patients with an indication for PICC placement can be included. Patients will be randomised into two groups, one with ECG-guided placement followed by ultrasound control and the other with only ultrasound guided placement. After placement, in both groups, control radiography of the chest will be done which will be interpreted by an independent radiologist. For the ECG-guided group the ultrasound control of the tip position will be done by an independent, blind operator, after placement. For the only ultrasound guided placement group, the ultrasound will be done by a second operator during placement.

Study Timeline

• Study First Submitted: 2015-05-26
• Study Start: 2015-06
• Study First Submitted QC: 2015-06-08
• Study First Posted: 2015-06-09
• Primary Completion: 2017-11
• Study Completion: 2017-11
• Status Verified: 2019-04
• Last Update Submitted: 2019-04-16
• Last Update Posted: 2019-04-17

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

• All adults with indication for PICC

Exclusion Criteria

• Age <18y
• Pregnant women

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
ULTRASOUND-guided insertion of PICC	ECG-guided insertion of PICC	Placement of the PICC (Peripherally Inserted Central Catheter ) ULTRASOUND-guided.
ULTRASOUND-guided insertion of PICC	ULTRASOUND-guided insertion of PICC	Placement of the PICC (Peripherally Inserted Central Catheter ) ULTRASOUND-guided.
ECG-guided insertion of PICC	ULTRASOUND-guided insertion of PICC	Placement of the PICC (Peripherally Inserted Central Catheter ) ECG-guided insertion.
ECG-guided insertion of PICC	ECG-guided insertion of PICC	Placement of the PICC (Peripherally Inserted Central Catheter ) ECG-guided insertion.

Primary Outcome Measures

Name	Time	Method
Number of participants with correct placement in the superior caval vein during PICC insertion, after either ECG or ultrasound guided insertion	Whitin 5 minutes after catheter-placement	The aim of the study is a comparison between two techniques to control correct positioning of the PICC

Secondary Outcome Measures

Name	Time	Method
Duration of PICC-placement by ECG-guidance versus ultrasound-guidance	within 5 minutes
frequency of necessity of replacement after chest-x-ray control	1 day	PICC tip should be located in the superior caval vein, close to the entrance of the right atrium. Other locations lead to repositioning.

Trial Locations

Locations (1)

Universitair Ziekenhuis Brussel; 🇧🇪 Jette, Brussels, Belgium