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临床试验/NCT01974583
NCT01974583已完成不适用

Wound-healing Improvement by Resurfacing Split-Thickness Skin Donor Sites With Thin Split-thickness Grafting

Tang-Du Hospital0 个研究点目标入组 192 人开始时间: 2002年1月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
192
主要终点
The time of epithelialization

研究概览

简要总结

Split-thickness skin grafting remains fundamental treatment of patients with deep burns and other traumatic injuries. However, the split-thickness skin graft (STSG) donor site dressing has been controversial until now. Our study here aimed to assess patient comfort and wound-healing efficacy with the application of thin split-thickness grafting on STSG donor sites.

详细描述

Background:Split-thickness skin grafting remains fundamental treatment of patients with deep burns and other traumatic injuries. However, the split-thickness skin graft (STSG) donor site dressing has been controversial until now. Our study here aimed to assess patient comfort and wound-healing efficacy with the application of thin split-thickness grafting on STSG donor sites.

Methods: 192 consecutive patients undergoing split-thickness skin grafting were included in the study and the participants were randomly divided into three groups: Group A was regrafted with thin STSG, while, Group B and Group C were covered with the occlusive hydrocellular dressing and paraffin gauze, respectively. The three groups were compared regarding to the time of epithelialization, pain sensed by the patients and the scar formation.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Prospective

入排标准

年龄范围
5 Years 至 56 Years(Child, Adult)
性别
All
接受健康志愿者

入选标准

  • patients who continuously received an STSG from January 2002 to December 2010 in Department of Burn and Plastic Surgery, Tangdu Hospital, Fourth Military Medical University

排除标准

  • The patients who were significant psychiatric, hypersensitive to silver, and not be followed up were excluded

结局指标

主要结局

The time of epithelialization

时间窗: up to 4 weeks

The time of epithelialization was observed every 3 days

次要结局

  • Pain sensed by the patients(up to 6 months)

研究者

发起方
Tang-Du Hospital
申办方类型
Other
责任方
Principal Investigator
主要研究者

Yongqian Bian

Mr Yongqian Bian

Tang-Du Hospital

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