Assessment of lactic acidosis associated with Metformin useage in Diabetic patients undergoing coronary angiography

Alborz University of Medical Sciences0 个研究点目标入组 200 人开始时间: 待定最近更新: 2020年5月18日

适应症

试验速览

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•Patient with type 2 diabetes who has undergone coronary angiography
•The GFR before angiography is equal to or greater than 60 ml per minute
•Patient with diabetes with a history of metformin usage
•Patient's Ejection Fraction is equal to or greater than 45%
•Patient's systolic blood pressure is equal to or greater than 90 mm Hg
•Serum creatinine levels before angiography are less than 1.49 mg in males and less than 1.40 mg / ml in females
•The patient's plasma pH should be 7.45-7.35 before angiography

•Critical physical condition requires immediate intervention
•Failure to perform PH or creatinine sampling and lactate levels after angiography
•Sepsis and other conditions that cause lactic acidosis
•Discontinuation of metformin usage by the patient
•Diarrhea, vomiting, and other conditions that predispose the patient to dehydration
•Increase serum creatinine by more than 1.5 mg / d

发起方

Alborz University of Medical Sciences