A phase II trial of induction CDDP plus TS-1 with concurrent radiotherapy followed by surgical resection in patients with pathologically confirmed stage IIIA-N2 squamous-cell non-small cell lung cancer
- Conditions
- Stage IIIA-N2 Squamous, Non-small cell lung cancer
- Registration Number
- JPRN-UMIN000012413
- Lead Sponsor
- Advanced Clinical Trial chest surgery Group (ACTG)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 80
Not provided
(1) Uncontrollable systemic disease (hyper tension, diabetes mellitus etc.) (2) Current history of hemosputum or hemoptysis (3) Evidence of bleeding diathesis or coagulopathy (4) Cavity in lung tumor or great vessel involvement (5) Current or previous (within the last 1 year) history of cerebrovascular disease (6) Traumatic fracture of un recovery (7) History of active infection (8) Hepatitis Bc antibody or hepatitis Bs antigen positive (9) Therapeutic anticoagulation; regular use of aspirin (>325 mg/day) (10) Severe GI disease (11) Current or previous (within the last 1 year) history of GI perforation or diverticultis (12) History of severe heart disease (13) Severe diarrhea (14) Severe drug allergy (15) Investigational new drug or the unapproved drug is administered (16) Interstitial pneumonia or pulmonary fibrosis detectable on chest Xp (17) History of active double cancer (18) History of pregnancy or lactation (19) Any other medical condition that makes the patient unsuitable for inclusion in the study according to the opinion of the investigator
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method