Comparison of a Water-soluble Topical Antimicrobial to Silver Sulfadiazine in Partial Thickness Burns
- Registration Number
- NCT01926392
- Lead Sponsor
- University of Virginia
- Brief Summary
Partial thickness burns are a common, painful injury requiring a great deal of resources in their care. Silver sulfadizine is a commonly-used topical antimicrobial, but is difficult to remove due to its lipid base. We are comparing a water-based topical antimicrobial therapy to silver sulfadiazine and hypothesize that the water-based therapy is superior in terms of pain control and resources required to deliver care.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 8
- adult inpatients with partial thickness burns
- superficial or full thickness burns, facial burns, intubated or sedated, pediatric
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Arm && Interventions
Group Intervention Description water-soluble therapy water-soluble therapy The patient acted as their own control and the experimental and comparison arms (water-soluble therapy and silver sulfadiazine) were alternated on a daily basis water-soluble therapy silver sulfadiazine The patient acted as their own control and the experimental and comparison arms (water-soluble therapy and silver sulfadiazine) were alternated on a daily basis silver sulfadiazine water-soluble therapy The patient acted as their own control and the experimental and comparison arms (water-soluble therapy and silver sulfadiazine) were alternated on a daily basis silver sulfadiazine silver sulfadiazine The patient acted as their own control and the experimental and comparison arms (water-soluble therapy and silver sulfadiazine) were alternated on a daily basis
- Primary Outcome Measures
Name Time Method Pain level 180 minutes Pain is assessed on a 0-10 point scale using both the patient's reported value and correlating with the value derived from nursing assessment using the visual analog scale. This is recorded at defined time points before, during, and after the dressing change
- Secondary Outcome Measures
Name Time Method time to perform dressing changes up to 180 minutes The time to perform the dressing change in total and for various steps is recorded in minutes.
Trial Locations
- Locations (1)
University of Virginia Health System
🇺🇸Charlottesville, Virginia, United States
University of Virginia Health System🇺🇸Charlottesville, Virginia, United States