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临床试验/NCT04633135
NCT04633135已完成不适用

Research on Emissions, Air Quality, Climate and Cooking Technologies in Northern Ghana

University of Colorado, Boulder0 个研究点目标入组 200 人开始时间: 2012年1月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
200
主要终点
Health (Biomarkers of inflammation)

研究概览

简要总结

REACCTING (Research on Emissions, Air quality, Climate, and Cooking Technologies in Northern Ghana) is an interdisciplinary randomized cookstove intervention study in the Kassena-Nankana District of Northern Ghana. The study tests two types of biomass burning stoves that have the potential to meet local cooking needs and represent different "rungs" in the cookstove technology ladder: a locally-made, low-tech Gyapa rocket stove and the imported, highly efficient Philips gasifier stove. Intervention households were randomized into four different groups, three of which received different combinations of two improved stoves, while the fourth group serves as a control for the duration of the study. Diverse measurements assess different points along the causal chain linking the intervention to final outcomes of interest. The investigators assess stove use and cooking behavior, cooking emissions, household air pollution and personal exposure, health burden, and local to regional air quality. Integrated analysis and modeling will tackle a range of interdisciplinary science questions, including examining ambient exposures among the regional population, assessing how those exposures might change with different technologies and behaviors, and estimating the comparative impact of local behavior and technological changes versus regional climate variability and change on local air quality and health outcomes.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Basic Science
盲法
None

入排标准

年龄范围
0 Years 至 55 Years(Child, Adult)
性别
All
接受健康志愿者
是

入选标准

  • •Individual Participants:
  • •Classified as "rural"
  • •Uses biofuel as main cooking fuel source (firewood, animal waste, crop residue/sawdust)
  • •Uses borehole as main water source (to facilitate social network analysis linking household's knowledge and attitudes toward stoves to experience of social contacts);
  • •Does not have electricity (to permit possible addition of lighting intervention at a later date);
  • •Has a woman in household aged 18-55 and at least one child under five (since women and children are the most vulnerable to cookstove smoke and are thus the main focus of our health measures).
  • •No more than 25% classified as urban
  • •Accessible year-round (determined by field staff)
  • •Having at least 10 eligible households (in line with the participant criteria above)

排除标准

  • •Household could not be located
  • •Household declined to participate

研究组 & 干预措施

Gyapa/Philips

Experimental

Households enrolled in the Gyapa/Philips arm of the study received one Gyapa stove and one Philips stove for free

干预措施: Philips stove (Device)

Gyapa/Philips

Experimental

Households enrolled in the Gyapa/Philips arm of the study received one Gyapa stove and one Philips stove for free

干预措施: Gyapa stove (Device)

Control

No Intervention

Households enrolled in the control arm of the study did not receive either improved cookstove

Gyapa/Gyapa

Experimental

Households enrolled in the Gyapa/Gyapa arm of the study received two Gyapa stoves for free

干预措施: Gyapa stove (Device)

Philips/Philips

Experimental

Households enrolled in the Philips/Philips arm of the study received two Philips stoves for free

干预措施: Philips stove (Device)

结局指标

主要结局

Health (Biomarkers of inflammation)

时间窗: At 18 months

Health indicators from blood spot samples (C-Reactive Protein, Sicam, sVCAM, serum amyloid A, Interleukin-1b, Interleukin-6, Interleukin-8, tumor necrosis factor alpha).

Height

时间窗: At 18 months

Height of participants

Weight

时间窗: At 18 months

Weight of participants

Mid-arm circumference

时间窗: At 18 months

Measurement of mid-upper arm circumference of participants

Weight

时间窗: At 6 months

Weight of participants

Health (Biomarkers of inflammation)

时间窗: At baseline

Health indicators from blood spot samples (C-Reactive Protein, Sicam, sVCAM, serum amyloid A, Interleukin-1b, Interleukin-6, Interleukin-8, tumor necrosis factor alpha).

Health (Biomarkers of inflammation)

时间窗: At 6 months

Health indicators from blood spot samples (C-Reactive Protein, Sicam, sVCAM, serum amyloid A, Interleukin-1b, Interleukin-6, Interleukin-8, tumor necrosis factor alpha).

Health (Biomarkers of inflammation)

时间窗: At 12 months

Health indicators from blood spot samples (C-Reactive Protein, Sicam, sVCAM, serum amyloid A, Interleukin-1b, Interleukin-6, Interleukin-8, tumor necrosis factor alpha).

Height

时间窗: At baseline

Height of participants

Height

时间窗: At 6 months

Height of participants

Height

时间窗: At 12 months

Height of participants

Weight

时间窗: At baseline

Weight of participants

Weight

时间窗: At 12 months

Weight of participants

Mid-arm circumference

时间窗: At baseline

Measurement of mid-upper arm circumference of participants

Mid-arm circumference

时间窗: At 6 months

Measurement of mid-upper arm circumference of participants

Mid-arm circumference

时间窗: At 12 months

Measurement of mid-upper arm circumference of participants

次要结局

  • Personal exposure to fine particulate matter (PM2.5)(48 hour deployment periods)
  • Personal exposure to carbon monoxide (CO)(48 hour deployment periods)
  • Kitchen area concentrations of carbon monoxide (CO)(48 hour deployment periods)
  • Kitchen area concentrations of fine particulate matter (PM2.5)(48 hour deployment periods)
  • Self-reported stove usage(At 18 months)
  • Stove usage as measured by devices(Throughout data collection period, approximately 2 years.)
  • Self-reported stove usage(At baseline)
  • Self-reported stove usage(At 6 months)
  • Self-reported stove usage(At 12 months)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Michael Hannigan

Principle Investigator

University of Colorado, Boulder

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