Effect of Tripterygium wilfordii polyglycoside tablets on the inhibition of TM on complement pathway and related inflammatory markers in membranous nephropathy

Phase 1

• Conditions: idiopathic membranous nephropathy

• Registration Number: ITMCTR2000003816
• Lead Sponsor: onghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

1. The clinical and pathological diagnosis was membranous nephropathy;
2. Aged 18-90 years old;
3. the patient was hospitalized within 24 hours after the onset of the disease;
4. there was no history of heart, liver dysfunction, severe anemia, leucopenia and thrombocytopenia.

Exclusion Criteria

1. acute and chronic kidney diseases other than membranous nephropathy;
2. long-term immobilization;
3. recent surgery and blood transfusion;
4. incomplete clinical data;
5. heart and liver dysfunction;
6. severe anemia, leukopenia and thrombocytopenia;
7. patients with active gastric and duodenal ulcer;
8. severe arrhythmia;
9. children, child-bearing age with pregnancy requirements, pregnant women and lactation woman.

Study & Design

• Study Type: Diagnostic test
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
CH50;Single complement component content;