In vitro drug-free activation (IVA) of the ovarian cortex and its re-transplantation in infertile women with reduced ovarian reserve
Phase 2
Completed
- Conditions
- Infertile women with reduced ovarian reserve.Female infertility
- Registration Number
- IRCT20221016056198N3
- Lead Sponsor
- Shahid Beheshti University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 15
Inclusion Criteria
Patients with age less than 40 years had decreased ovarian reserve based on POSEIDON group 3 and 4 criteria
AMH less than 1 mg/dl
Fsh less than 10
with a history of at least one failed stimulation cycle resulting in the inability to retrieve oocyte
Exclusion Criteria
male factor infertility
positive history of hydrosalpinx
anatomical uterine disorders
endocrine disease
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie drug-free ovarian cortex activation in IRCT20221016056198N3?
How does in vitro ovarian cortex activation compare to standard fertility treatments for reduced ovarian reserve?
What biomarkers are used to select patients for in vitro ovarian cortex re-transplantation in phase II trials?
What are the potential adverse events associated with drug-free ovarian cortex re-transplantation?
Are there any combination therapies or competitor drugs being studied for drug-free ovarian activation in infertility?