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临床试验/NCT07678476
NCT07678476已完成不适用

Effects of Single-Session Brisk Walking and Baduanjin Exercise on Inhibitory Function in Older Adults With Cognitive Impairment: An Exploration of Resting-State EEG Mechanisms

Shanghai University of Sport1 个研究点 分布在 1 个国家目标入组 45 人开始时间: 2025年8月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
45
试验地点
1
主要终点
Change in Inhibitory Function Assessed by the Stroop Color-Word Test

研究概览

简要总结

This study aims to investigate the acute effects of single-session different forms of aerobic exercise (brisk walking and Baduanjin) on inhibitory function and resting-state EEG power in older adults with cognitive impairment, providing scientific evidence for developing exercise intervention programs for this population.

Specifically, this study seeks to answer the following core questions:

  1. Can a single session of brisk walking and a single session of Baduanjin exercise improve reaction time and accuracy on the Stroop color-word task in older adults with cognitive impairment?
  2. Are there differential effects on inhibitory function between the two exercise modalities?
  3. Does a single exercise session induce immediate changes in resting-state EEG power spectrum across multiple frequency bands (δ, θ, α, β)?
  4. Are changes in resting-state EEG power associated with improvements in inhibitory function?

Forty-five older adults with cognitive impairment will be randomly assigned to three groups (n=15 each): brisk walking group, Baduanjin group, and control group (quiet seated rest). Participants in the brisk walking and Baduanjin groups will each perform a single 30-minute moderate-intensity exercise session. All participants will complete the Stroop color-word task (assessing reaction time and accuracy under both congruent and incongruent conditions) and undergo a 5-minute eyes-closed resting-state EEG recording before and immediately after the intervention.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
60 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者
否

入选标准

  • •Age ≥ 60 years, regardless of gender;
  • •Right-handed;
  • •Montreal Cognitive Assessment (MoCA) score ≤ 25;
  • •Normal or corrected-to-normal vision;
  • •Normal hearing;
  • •Signed informed consent.

排除标准

  • •Presence of severe cognitive impairment or other neurodegenerative diseases;
  • •Presence of psychiatric disorders, or current or long-term use of psychotropic medications;
  • •Presence of severe cardiovascular diseases (e.g., heart failure, atherosclerosis, myocardial infarction, etc.);
  • •Presence of severe muscle diseases, or a history of lower limb injury within the past six months that would preclude the ability to stand for extended periods.

研究组 & 干预措施

control group

No Intervention

brisk walking group

Experimental

Single exercise session, duration 30 minutes

干预措施: exercise intervention (Behavioral)

Baduanjin group

Experimental

Single exercise session, duration 30 minutes

干预措施: exercise intervention (Behavioral)

结局指标

主要结局

Change in Inhibitory Function Assessed by the Stroop Color-Word Test

时间窗: Baseline and immediately post-intervention (approximately 30 minutes after the exercise session)

Inhibitory function will be assessed using the Stroop color-word test. Participants are required to name the color of the ink while inhibiting the automatic tendency to read the word. The outcome measure is the change from baseline in accuracy rate (%) under both congruent and incongruent conditions immediately post-intervention.

Change in Inhibitory Function Assessed by the Stroop Color-Word Test

时间窗: Baseline and immediately post-intervention (approximately 30 minutes after the exercise session

Inhibitory function will be assessed using the Stroop color-word test. Participants are required to name the color of the ink while inhibiting the automatic tendency to read the word. The outcome measure is the change from baseline in reaction time (milliseconds) under both congruent and incongruent conditions immediately post-intervention.

次要结局

  • Change in Resting-State EEG Power Spectrum(Baseline and immediately post-intervention (approximately 30 minutes after the exercise session))

研究者

发起方
Shanghai University of Sport
申办方类型
Other
责任方
Principal Investigator
主要研究者

Ding Feng

Director

Shanghai University of Sport

研究点 (1)

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