Impact of Duration of Untreated Manic Episodes on Clinical Outcome

• Conditions: Patients Diagnosed With Bipolar Disorder ( Manic Episodes) and Delayed Diagnosis
• Interventions: Other: young mania rating scale

• Registration Number: NCT04563910
• Lead Sponsor: Assiut University

Brief Summary

The current study is cross sectional retrospective study, included 100 patients were diagnosed as mood disorder bipolar I (manic episodes) according to DSM5, patients recruited from inpatient psychiatric unit at department of Neurology and Psychiatry, Assiut University hospitals The current work is designed to study the effect of duration of untreated bipolar disorder on clinical outcome ( severity , residual symptoms ,duration of hospital admission) and to study factors affecting duration of untreatment in Upper Egypt.

Detailed Description

Mood disorder carries a major burden in our country as it represents 15% of inpatients and 20% of outpatients in mental hospitals in Egypt

The current work is designed to study the effect of duration of untreated bipolar disorder on clinical outcome ( severity , residual symptoms ,duration of hospital admission) and to study factors affecting duration of untreatment in Upper Egypt.

The current study is cross sectional retrospective study, included 100 patients were diagnosed as mood disorder bipolar I (manic episodes) according to DSM5, patients recruited from inpatient psychiatric unit at department of Neurology and Psychiatry, Assiut University hospitals

Study Timeline

• Status Verified: 2020-09
• Study First Submitted: 2020-09-19
• Study First Submitted QC: 2020-09-19
• Last Update Submitted: 2020-09-19
• Study Start: 2020-09-23
• Study First Posted: 2020-09-25
• Last Update Posted: 2020-09-25
• Primary Completion: 2021-09-23
• Study Completion: 2021-10-24

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• -Age group between 18 to 45 years old.
• Patients diagnosed as mood disorder bipolar I manic episode according to DSM V(2).
• Clearly consenting to participate in the study.

Exclusion Criteria

• -Mood disorder due to substance abuse.
• Patients in depressive episodes.
• other mental disorders

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
less than 2 episodes	young mania rating scale	Patients were classified into 3 groups according to number of episodes (1-2 episodes, 3-5 episodes, more than 5 episodes)
2-5 episodes	young mania rating scale	Patients were classified into 3 groups according to number of episodes (1-2 episodes, 3-5 episodes, more than 5 episodes)
more than 5 episodes	young mania rating scale	Patients were classified into 3 groups according to number of episodes (1-2 episodes, 3-5 episodes, more than 5 episodes)

Primary Outcome Measures

Name	Time	Method
measure the effect of duration of untreated bipolar disorder on severity (young mania rating scale on admission	one year	To study the effect of duration of untreated bipolar disorder (manic episodes) on clinical outcomes (severity).

Secondary Outcome Measures

Name	Time	Method
To measure the effect of duration of untreated bipolar disorder (manic episodes) on clinical outcomes (severity, residual symptoms, duration of admission).	one year	residual symptoms measured by young mania rating scale on discharge

Trial Locations

Locations (1)

Assiut university; 🇪🇬 Assiut, Egypt