Role of vitamin-D supplementation in addition to standard treatment of asthma in childre
Not Applicable
Completed
- Conditions
- Health Condition 1: null- Children of Asthma coming to paediatric OPDHealth Condition 2: J454- Moderate persistent asthma
- Registration Number
- CTRI/2018/07/014777
- Lead Sponsor
- AIIMS Jodhpur
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
1. Children 6 to 18 years of age, newly diagnosed case of asthma by Pediatrician. (Clinical and/or PFT). OR follow-up case of asthma in chest clinic at AIIMS
2. Those willing to take medication for 3 months and regular follow-up.
Exclusion Criteria
1. Patients with history of prematurity, bronchopulmonary dysplasia, coexisting primary parenchymal pulmonary disease (e.g. cystic fibrosis) or coexisting congenital/acquired heart diseases, and patients of epilepsy on anticonvulsants.
2. Known case of Vitamin â??D deficiency.
3. History of intake of Vitamin-D and calcium in past 1 month.
4. Known case of any disease involving Vitamin-D & calcium metabolism.
5. Consent not given.
6. Those with hypercalcemia or allergy to Vitamin- D.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.Primary outcome measure will be ACT score (which is a validated score and contained 5 items with minimum score of 5 to maximum score of 25) at 3 monthsTimepoint: 1.Enrollment will be done in 1st 3 months <br/ ><br>2.Interventions will start at the time of enrollment. <br/ ><br>3.Participants will be asked to visit clinic after every 15 days for follow-up. <br/ ><br>
- Secondary Outcome Measures
Name Time Method Secondary outcome measure will be FEV1, fraction excretion of nitric oxide, number of asthma exacerbation, serum 25-OH vitamin D3 at 3 months and adverse outcome, no. of emergency visits, use of systemic steroid.Timepoint: 1.Enrollment will be done in 1st 3 months <br/ ><br>2.Interventions will start at the time of enrollment. <br/ ><br>3.Participants will be asked to visit clinic after every 15 days for follow-up. <br/ ><br>