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Clinical Trials/NCT03594812
NCT03594812
Completed
Not Applicable

Effect of Aerobic Exercise Associated With Abdominal Radiofrequency on on Adipose Tissue in Women: Randomized Controlled Trial

Escola Superior de Tecnologia da Saúde do Porto1 site in 1 country30 target enrollmentJuly 15, 2018

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Cardiovascular Risk Factor
Sponsor
Escola Superior de Tecnologia da Saúde do Porto
Enrollment
30
Locations
1
Primary Endpoint
Subcutaneous abdominal tissue thickness
Status
Completed
Last Updated
7 years ago

Overview

Brief Summary

The purpose of the present study was to evaluate the effects of one session of aerobic exercise associated with radiofrequency in lipolytic activity and lipid profile.

Detailed Description

The adipose tissue is the main energetic reserve, being constituted by adipocytes, cells that accumulate lipids inside its cytoplasm, in the form of triglycerides. Fat deposition can occur both in the subcutaneous compartment and in the visceral compartment and is the result of a positive energy balance in which there is an imbalance between the amount of calories consumed and the amount of calories expended. Thus, an excess of energy storage occurs in the form of triglycerides in adipose tissue, which results from a sedentary lifestyle and a diet based on lipid rich nutrients. When fat deposition occurs in abdominal adipose tissue may favor the development of metabolic disorders. Recently the effectiveness of an innovative physiotherapeutic intervention - radiofrequency on adipose tissue has been studied. This therapeutic modality stimulates the lipolytic cascade, converting the triglycerides to fatty acids and glycerol. In this way, radiofrequency seems to aid in the reduction of adiposity. In addition, it assists in the reduction of the inflammatory process related to obesity, by reducing the pro-inflammatory cytokines. The aerobic exercise, due to its low-moderate intensity, enhances the stimulation of lipolysis, by decreasing plasma insulin concentration and elevating the level of catecholamines. In this way, it influences the lipid metabolism, seeming to improve the lipid profile, through the degradation of the triglycerides as energetic substrate. In addition, the regular practice of physical exercise seems to promote a decrease in the inflammation state due to metabolic changes, through the reduction of pro-inflammatory cytokines, namely interleukin-6 and, consequently, C-reactive protein. This study purpose understanding whether an aerobic exercise session associated with abdominal radiofrequency increases the level of lipolytic activity; To analyse the effect of four intervention sessions on abdominal adipose tissue

Registry
clinicaltrials.gov
Start Date
July 15, 2018
End Date
September 20, 2018
Last Updated
7 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Andreia Noites

Professor

Escola Superior de Tecnologia da Saúde do Porto

Eligibility Criteria

Inclusion Criteria

  • Body Mass Idex between 18,5 Kg/cm2 and 29,9 Kg/cm2

Exclusion Criteria

  • pregnant or intending to be in a period of an year
  • participants with smoking habits
  • participants with neoplasias, metabolic dysfunctions, renal pathologies, dermatological alterations
  • participants with electronic devices
  • participants with a condition that makes it impossible to practice physical exercise (disabling skeletal muscle pathologies and severe cardiorespiratory pathologies) participants under the effect of beta-blockers or other drugs which influence heart rate participants submitted to other fat reduce procedure

Outcomes

Primary Outcomes

Subcutaneous abdominal tissue thickness

Time Frame: before intervention and 2 week after (after 4 sessions of intervention )

Measurement of the subcutaneous adipose fold by ultrasonography

Change in glycerol concentration

Time Frame: 10 minutes before the intervention and 5 minutes after the intervention

Blood analysis collection was carried out with help from an clinical analysis technician.

Secondary Outcomes

  • Change in lipid profile (LDL, HDL and triglyceride concentrations)(10 minutes before the intervention and 5 minutes after the intervention)

Study Sites (1)

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