Effect of Aerobic Exercise Associated With Abdominal Radiofrequency on on Adipose Tissue in Women: Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- Subcutaneous abdominal tissue thickness
研究概览
简要总结
The purpose of the present study was to evaluate the effects of one session of aerobic exercise associated with radiofrequency in lipolytic activity and lipid profile.
详细描述
The adipose tissue is the main energetic reserve, being constituted by adipocytes, cells that accumulate lipids inside its cytoplasm, in the form of triglycerides.
Fat deposition can occur both in the subcutaneous compartment and in the visceral compartment and is the result of a positive energy balance in which there is an imbalance between the amount of calories consumed and the amount of calories expended. Thus, an excess of energy storage occurs in the form of triglycerides in adipose tissue, which results from a sedentary lifestyle and a diet based on lipid rich nutrients. When fat deposition occurs in abdominal adipose tissue may favor the development of metabolic disorders.
Recently the effectiveness of an innovative physiotherapeutic intervention - radiofrequency on adipose tissue has been studied. This therapeutic modality stimulates the lipolytic cascade, converting the triglycerides to fatty acids and glycerol. In this way, radiofrequency seems to aid in the reduction of adiposity. In addition, it assists in the reduction of the inflammatory process related to obesity, by reducing the pro-inflammatory cytokines.
The aerobic exercise, due to its low-moderate intensity, enhances the stimulation of lipolysis, by decreasing plasma insulin concentration and elevating the level of catecholamines. In this way, it influences the lipid metabolism, seeming to improve the lipid profile, through the degradation of the triglycerides as energetic substrate. In addition, the regular practice of physical exercise seems to promote a decrease in the inflammation state due to metabolic changes, through the reduction of pro-inflammatory cytokines, namely interleukin-6 and, consequently, C-reactive protein.
This study purpose understanding whether an aerobic exercise session associated with abdominal radiofrequency increases the level of lipolytic activity; To analyse the effect of four intervention sessions on abdominal adipose tissue
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Body Mass Idex between 18,5 Kg/cm2 and 29,9 Kg/cm2
排除标准
- •pregnant or intending to be in a period of an year
- •participants with smoking habits
- •participants with neoplasias, metabolic dysfunctions, renal pathologies, dermatological alterations
- •participants with electronic devices
- •participants with a condition that makes it impossible to practice physical exercise (disabling skeletal muscle pathologies and severe cardiorespiratory pathologies) participants under the effect of beta-blockers or other drugs which influence heart rate participants submitted to other fat reduce procedure
研究组 & 干预措施
Experimental group
This group performed aerobic exercise just after radiofrequency therapy in the abdominal region.
干预措施: Radiofrequency (Device)
Experimental group
This group performed aerobic exercise just after radiofrequency therapy in the abdominal region.
干预措施: Aerobic exercise (Device)
Placebo group
This group performed aerobic exercise just after radiofrequency therapy in the abdominal region but the radiofrequency device was switched off- Radiofrequency without power.
干预措施: Radiofrequency without power (Device)
Placebo group
This group performed aerobic exercise just after radiofrequency therapy in the abdominal region but the radiofrequency device was switched off- Radiofrequency without power.
干预措施: Aerobic exercise (Device)
结局指标
主要结局
Subcutaneous abdominal tissue thickness
时间窗: before intervention and 2 week after (after 4 sessions of intervention )
Measurement of the subcutaneous adipose fold by ultrasonography
Change in glycerol concentration
时间窗: 10 minutes before the intervention and 5 minutes after the intervention
Blood analysis collection was carried out with help from an clinical analysis technician.
次要结局
- Change in lipid profile (LDL, HDL and triglyceride concentrations)(10 minutes before the intervention and 5 minutes after the intervention)
研究者
Andreia Noites
Professor
Escola Superior de Tecnologia da Saúde do Porto