Effect of Percutaneous Botulinum Toxin A Injection on Natural Course of Upper Lid Retraction in Thyroid Eye Disease

Phase 2

• Conditions: Eye Diseases

• Registration Number: NCT00370734
• Lead Sponsor: Shahid Beheshti University of Medical Sciences

Brief Summary

In active phase of thyroid eye disease some patients have obvious upper lid retraction , and sometimes exposure keratopathy .To date there is not any standard treatment for this situation . We are going to compare the natural course of the upper lid retraction with injection of botulinum toxin A injection to upper lid percutaneously.

Detailed Description

Not available

Study Timeline

• Study Start: 2005-05
• Study First Submitted: 2006-08-31
• Study First Submitted QC: 2006-08-31
• Study First Posted: 2006-09-01
• Status Verified: 2007-02
• Study Completion: 2007-02
• Last Update Submitted: 2007-02-26
• Last Update Posted: 2007-02-27

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• all the patients wiht oper lid retraction in active phase of thyroid ophthalmopathy

Exclusion Criteria

• patients in non active phase

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Trial Locations

Locations (1)

Babak Babsharif, MD; 🇮🇷 Tehran, Iran, Islamic Republic of