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Platelet phenotyping by immunofluorescence microscopy on the blood smear in subjects with myeloprolipherative disorders

Recruiting
Conditions
D50-D89
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
Registration Number
DRKS00032588
Lead Sponsor
Klinik für Innere Medizin C, Universitätsmedizin Greifswald
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
200
Inclusion Criteria

Ensured diagnosis of clonal, myeloid disorder (CHIP, CCUS, ICUS, MDS, MPN, MDS-MPN-Overlap, CML or MDS/AML according to WHO), as well as healthy controls.

Exclusion Criteria

None.

Study & Design

Study Type
observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
To identify possible correlations between platelet phenotype determined by light- and immunofluorescence microscopy and clinical or genetic characteristics of MPN patients that may be diagnostically and prognostically relevant.
Secondary Outcome Measures
NameTimeMethod
To distinguish MPN patients from healthy controls, based on the found correlations described in the primary endpoint.
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