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临床试验/NCT03249961
NCT03249961已完成不适用

How Many Days Would You Want to Practice a Skill to Achieve it?

Sunnybrook Health Sciences Centre1 个研究点 分布在 1 个国家目标入组 27 人开始时间: 2018年4月20日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
27
试验地点
1
主要终点
Accuracy

研究概览

简要总结

Practice is required to improve your shot in basketball or to play a musical instrument. The learning of these motor skills can be further enhanced by non-invasively stimulating regions of the brain that control movements with electrical currents. These electric currents can strengthen or weaken connections of the brain, which consequently affects a person's ability to improve their performance on a skill. Non-invasive brain stimulation (NIBS) is widely applied in many disciplines of neuroscience research, and has potential therapeutic application. There are two specific types of NIBS that will be used in this research study: 1) Transcranial Direct Current Stimulation (tDCS), which applies very weak electrical currents via two rubber electrodes on the scalp, and 2) Transcranial Magnetic Stimulation (TMS), which applies magnetic pulses via a coil against the head, to stimulate regions of the brain. Both types of non-invasive brain stimulation (i.e., tDCS, and TMS) are well-tolerated, painless, and safe. The application of tDCS to brain regions that control movements, concurrently with practice of a skill, results in better skill performance, than practice alone with no tDCS. Therefore, in this study, we will be testing different types of brain stimulation and different amounts of practice.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Basic Science
盲法
Single (Participant)

入排标准

年龄范围
18 Years 至 44 Years(Adult)
性别
All
接受健康志愿者
是

入选标准

  • 未提供

排除标准

  • •prior history of neurological or psychiatric disease
  • •prior experience with the motor task used
  • •contraindications to TMS and TDCS (e.g., metal implants, history of seizures and headaches)
  • •musculoskeletal injury to upper limb
  • •drugs that interact with NIBS (e.g., antidepressants, antipsychotics, anticonvulsants)

研究组 & 干预措施

Placebo Brain stimulation

Experimental

Participants will receive Sham TDCS, and Transcranial Magnetic Stimulation (TMS)

干预措施: Sham TDCS (Device)

Placebo Brain stimulation

Experimental

Participants will receive Sham TDCS, and Transcranial Magnetic Stimulation (TMS)

干预措施: Transcranial Magnetic Stimulation (TMS) (Device)

Excitatory Brain Stimulation

Experimental

Participants will receive Anodal TDCS, and Transcranial Magnetic Stimulation (TMS)

干预措施: Anodal TDCS (Device)

Excitatory Brain Stimulation

Experimental

Participants will receive Anodal TDCS, and Transcranial Magnetic Stimulation (TMS)

干预措施: Transcranial Magnetic Stimulation (TMS) (Device)

结局指标

主要结局

Accuracy

时间窗: Up to 8 days

Accuracy is defined as the proportion of trials per block with hits to all targets in the correct sequence order.

Speed

时间窗: Up to 8 days

Speed is captured by the average sequence movement time per training block

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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